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局限性儿童外阴类天疱疮:一项罕见病例研究。

Localised childhood vulvar pemphigoid: a rare case study.

作者信息

Peeters A S, Dhont N, Stals H

出版信息

Facts Views Vis Obgyn. 2021 Sep;13(3):279-282. doi: 10.52054/FVVO.13.3.031.

DOI:10.52054/FVVO.13.3.031
PMID:34555883
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8823273/
Abstract

In this case report we present a young patient with localised childhood vulvar pemphigoid. It is a rare variant of bullous pemphigoid with mostly a favourable prognosis and prompt response to potent topical corticosteroids. She presented with relapsing vulvar pain and lesions. Our case enlightens the recognition of this unusual subtype and the importance of performing a cutaneous biopsy.

摘要

在本病例报告中,我们介绍了一名患有局限性儿童外阴类天疱疮的年轻患者。这是大疱性类天疱疮的一种罕见变体,预后大多良好,对强效外用皮质类固醇反应迅速。她表现为复发性外阴疼痛和病变。我们的病例有助于认识这种不寻常的亚型以及进行皮肤活检的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87c8/8823273/65f8bbfab98c/FVVinObGyn-13-279-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87c8/8823273/1457d1808b35/FVVinObGyn-13-279-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87c8/8823273/65f8bbfab98c/FVVinObGyn-13-279-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87c8/8823273/1457d1808b35/FVVinObGyn-13-279-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87c8/8823273/65f8bbfab98c/FVVinObGyn-13-279-g002.jpg

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1
Localised childhood vulvar pemphigoid: a rare case study.局限性儿童外阴类天疱疮:一项罕见病例研究。
Facts Views Vis Obgyn. 2021 Sep;13(3):279-282. doi: 10.52054/FVVO.13.3.031.
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本文引用的文献

1
Efficacy of dapsone in the treatment of pemphigus and pemphigoid: analysis of current data.氨苯砜治疗天疱疮和类天疱疮的疗效:当前数据分析
Am J Clin Dermatol. 2009;10(6):383-96. doi: 10.2165/11310740-000000000-00000.
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Multicenter prospective study of the humoral autoimmune response in bullous pemphigoid.大疱性类天疱疮体液自身免疫反应的多中心前瞻性研究
Clin Immunol. 2008 Sep;128(3):415-26. doi: 10.1016/j.clim.2008.04.012. Epub 2008 Jun 20.
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An infant with bullous pemphigoid.一名患有大疱性类天疱疮的婴儿。
Dermatol Online J. 2007 Jul 13;13(3):17.
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Bullous pemphigoid in infancy: Clinical and epidemiologic characteristics.婴儿期大疱性类天疱疮:临床及流行病学特征
J Am Acad Dermatol. 2008 Jan;58(1):41-8. doi: 10.1016/j.jaad.2007.08.010. Epub 2007 Oct 22.
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Childhood bullous pemphigoid: a clinicopathologic study and review of the literature.儿童大疱性类天疱疮:一项临床病理研究及文献综述
Am J Dermatopathol. 2003 Jun;25(3):183-9. doi: 10.1097/00000372-200306000-00001.
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Vulvar disease in children: a clinical audit of 130 cases.儿童外阴疾病:130例临床审计
Pediatr Dermatol. 2000 Jan-Feb;17(1):1-6. doi: 10.1046/j.1525-1470.2000.01701.x.
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A child with localized vulval pemphigoid and IgG autoantibodies targeting the C-terminus of collagen XVII/BP180.
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Childhood vulval pemphigoid: a clinical and immunopathological study of five patients.儿童外阴类天疱疮:5例患者的临床及免疫病理学研究
Br J Dermatol. 1999 Feb;140(2):308-12. doi: 10.1046/j.1365-2133.1999.02668.x.
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Lichen planus pemphigoides is a heterogeneous disease: a report of five cases studied by immunoelectron microscopy.类天疱疮样扁平苔藓是一种异质性疾病:5例免疫电镜研究报告
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