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胸腺因子X(TFX)及抗TFX球蛋白对小鼠Lewis肺癌生长的影响。

The influence of thymus factor X (TFX) and of anti-TFX globulin on the growth of Lewis lung carcinoma in mice.

作者信息

Frackowiak J, Zółtowska A, Gan J

机构信息

Department of Physiopathology, Medical Academy, Gdańsk.

出版信息

Arch Immunol Ther Exp (Warsz). 1987;35(5):593-8.

PMID:3455648
Abstract

The influence of thymus factor X--TFX (Polfa) and an anti-TFX rabbit gammaglobulin (RATFX) on the growth of Lewis lung carcinoma in mice was studied. The preparations were administered subcutaneously into the peritumoral region. Tumor growth was significantly retarded in the RATFX-treated groups, while a low dose TFX therapy was ineffective. No significant differences in peritumoral inflammatory reaction in treated and untreated mice were found.

摘要

研究了胸腺因子X(TFX,波法药厂生产)和抗TFX兔丙种球蛋白(RATFX)对小鼠Lewis肺癌生长的影响。将制剂皮下注射到肿瘤周围区域。RATFX治疗组的肿瘤生长明显受到抑制,而低剂量TFX治疗无效。在治疗和未治疗的小鼠中,肿瘤周围炎症反应未发现显著差异。

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