Acute Medicine, Southend Hospital, Westcliff-on-Sea, UK
Acute Medicine, Southend Hospital, Westcliff-on-Sea, UK.
BMJ Case Rep. 2021 Sep 23;14(9):e245092. doi: 10.1136/bcr-2021-245092.
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a relatively novel term which describes patients who have developed a low platelet count and prothrombotic tendencies secondary to receiving a vaccine. The concept has been derived from the well-established phenomenon of heparin-induced thrombocytopenia, and several cases of VITT have now been reported in patients who have received the AstraZeneca (ChAdOx1 nCov-19) vaccine. Unfortunately, some of these patients have gone on to develop intracranial venous sinus thrombosis. We present a case of VITT-associated sinus thrombosis secondary to the AstraZeneca (ChAdOx1 nCov-19) vaccine, which was complicated by a large intracerebral haemorrhage.
疫苗诱导的免疫性血栓性血小板减少症（VITT）是一个相对较新的术语，用于描述因接种疫苗而导致血小板计数降低和血栓倾向的患者。这一概念源自已确立的肝素诱导性血小板减少症现象，目前已有几例 VITT 病例报告发生在接种阿斯利康（ChAdOx1 nCov-19）疫苗的患者中。不幸的是，其中一些患者进展为颅内静脉窦血栓形成。我们报告了一例继发于阿斯利康（ChAdOx1 nCov-19）疫苗的 VITT 相关的静脉窦血栓形成病例，该病例并发了大面积脑出血。
