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病例报告:婴儿混合性生殖细胞肿瘤的罕见表现。

Case Report: Rare Presentation of Mixed Germ Cell Tumor in an Infant.

作者信息

Talluri Sriharsha, Goedde Michael A, Coventry Susan, Rosenberg Eran, Canalichio Katie L, Peppas Dennis, White Jeffrey T

机构信息

Department of Urology, University of Louisville, Louisville, KY, United States.

Department of Pediatric Anatomic Pathology, Norton Healthcare, Louisville, KY, United States.

出版信息

Front Pediatr. 2021 Sep 7;9:729917. doi: 10.3389/fped.2021.729917. eCollection 2021.

Abstract

The estimated incidence of pediatric testis tumor is 0.5-2.0 per 100,000 children, accounting for 1-2% of all pediatric tumors. Mixed germ cell tumors (MGCT) in prepubertal males are exceedingly rare, with only one previous case report found in the literature. We report a case of a MGCT in an infant. For prepubertal males, GCTs typically present with a painless scrotal mass, though trauma, testis torsion and hydrocele are also common presentations. Similar to such tumors in postpubertal males, ultrasonography, computed tomography, and tumor markers are integral to determine the best treatment. The patient described in this report presented with a painless scrotal mass. Following orchiectomy, the patient was found to have MGCT that was limited to the testis. With prudent management, these patients tend to have favorable prognoses.

摘要

小儿睾丸肿瘤的估计发病率为每10万名儿童中有0.5 - 2.0例,占所有小儿肿瘤的1 - 2%。青春期前男性的混合性生殖细胞肿瘤(MGCT)极为罕见,文献中仅发现一例既往病例报告。我们报告一例婴儿MGCT病例。对于青春期前男性,生殖细胞肿瘤通常表现为无痛性阴囊肿块,不过创伤、睾丸扭转和鞘膜积液也是常见表现。与青春期后男性的此类肿瘤相似,超声、计算机断层扫描和肿瘤标志物对于确定最佳治疗至关重要。本报告中描述的患者表现为无痛性阴囊肿块。睾丸切除术后,发现该患者患有局限于睾丸的MGCT。通过谨慎管理,这些患者往往预后良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78a6/8453063/4c6505fbe1a6/fped-09-729917-g0001.jpg

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