Chair and Department of Dermatology, Venerology and Paediatric Dermatology, Faculty of Medicine, Medical University, Lublin, Poland.
Chair and Department of Internal Diseases, Faculty of Medicine, Medical University, Lublin, Poland.
Ann Agric Environ Med. 2021 Sep 16;28(3):525-530. doi: 10.26444/aaem/140594. Epub 2021 Aug 19.
Angioimmunoblastic T-cell lymphoma (AITL) is an uncommon lymphoma of elderly adults with a poor prognosis. AITL patients show systemic symptoms, lymphadenopathy, and not infrequently, skin rash with various dysimmune phenomena rashes. The case is presented of a 68-year-old male with skin rash, lymphadenopathy and hypereosinophilia who, after investigations, was diagnosed with AITL. Despite the treatment used, the patient's condition gradually deteriorated and died due to heart and kidney failure. The diagnosis of AITL is often established only after several weeks or months because of transient physical findings, non-specific symptoms, and a broad range of serologic or radiologic abnormalities. Some patients with AITL experience non-specific dermatitis and eosinophilia. The presented case should raise awareness of the presentations of AITL which is important for physicians to reach an accurate diagnosis.
血管免疫母细胞性 T 细胞淋巴瘤（AITL）是一种罕见的老年人群体中的淋巴瘤，预后较差。AITL 患者表现为全身症状、淋巴结病，并且常伴有多种免疫现象异常的皮疹。本文报道了 1 例 68 岁男性患者，其表现为皮疹、淋巴结病和嗜酸性粒细胞增多症，经检查后诊断为 AITL。尽管使用了治疗方法，但患者的病情逐渐恶化，最终因心、肾功能衰竭而死亡。由于一过性的体格检查结果、非特异性症状以及广泛的血清学或影像学异常，AITL 的诊断通常需要数周或数月后才能确定。一些 AITL 患者会出现非特异性的皮炎和嗜酸性粒细胞增多症。本病例应引起人们对 AITL 表现的认识，这对于医生做出准确诊断非常重要。
