Department of Hematology, Peking University First Hospital, Beijing 100034, China.
Department of Pathology, Peking University First Hospital, Beijing 100034, China.
Curr Oncol. 2022 Oct 13;29(10):7637-7644. doi: 10.3390/curroncol29100603.
Angioimmunoblastic T-cell lymphoma is one of the peripheral T-cell lymphomas. Reactive plasma cells can occasionally be observed in AITL patients' peripheral blood and bone marrow. Plasmacytic pleural effusion as the presentation of AITL has not been reported before. The mechanisms of plasmacytic pleural effusion are not fully understood. Here we present an 82-year-old male with exuberant plasma cells in his pleural effusion in addition to his peripheral blood and bone marrow aspiration. By presenting this case, we would like to expand the spectrum of disease presentations in AITL and discuss the significance of flow cytometry in the differential diagnosis of pleural effusion. To our knowledge, this is the first case report in the literature, which will be crucial to assist the hematopathologist in accurate diagnosis and treatment.
血管免疫母细胞性 T 细胞淋巴瘤是外周 T 细胞淋巴瘤的一种。反应性浆细胞偶尔可在外周血和骨髓中观察到血管免疫母细胞性 T 细胞淋巴瘤患者。浆细胞性胸腔积液作为血管免疫母细胞性 T 细胞淋巴瘤的表现以前尚未报道过。浆细胞性胸腔积液的发病机制尚未完全阐明。在此，我们介绍了一例 82 岁男性患者，其胸腔积液中除了外周血和骨髓抽吸物外，还有丰富的浆细胞。通过呈现该病例，我们希望扩展血管免疫母细胞性 T 细胞淋巴瘤的疾病表现谱，并讨论流式细胞术在胸腔积液鉴别诊断中的意义。据我们所知，这是文献中的首例病例报告，对于协助血液病理学家进行准确诊断和治疗至关重要。
