School of Health Sciences, Oakland University, 3114 Human Health Building, Rochester, MI, 48309, USA.
Department of Oncology, Wayne State University, Detroit, MI, USA.
J Immigr Minor Health. 2022 Oct;24(5):1095-1102. doi: 10.1007/s10903-021-01279-4. Epub 2021 Sep 24.
To estimate the age- and sex-adjusted proportions of cataract, diabetic retinopathy, glaucoma, and macular degeneration among the Arab American community, a notably understudied minority that is aggregated under whites. The Arab American Eye Study is a multicenter retrospective chart review involving 10 years of electronic medical records (1/1/2010 through 1/1/2020). The study sample included 1390 Arab Americans and 4950 whites 45 years of age and older, totaling 6340 subjects. Arab Americans were identified using an Arab American name algorithm. Subjects with race variables other than white or Arab American or those under age 45 were excluded from the study. Age- and sex-adjusted proportions of cataract, diabetic retinopathy, glaucoma, and macular degeneration were determined. Odds ratios with 95% confidence intervals were used to examine the association between race/ethnicity and eye diseases. Of the 6340 participants (4950 whites and 1390 Arab Americans), males comprised 46.3% and the median age group was 55-64 years. Arab Americans displayed higher age- and sex-adjusted proportions of cataracts (45.4% versus 40.7%), dry age-related macular degeneration (10% versus 8.9%), glaucoma (8% vs 6%), and diabetic retinopathy (11.7% versus 4.2%). Fully adjusted logistic regression revealed that Arab Americans were 19% more likely to have cataracts (OR 1.19; 95% CI 1.05, 1.35) and 272% more likely to have diabetic retinopathy (OR 2.72; 95% CI 2.17; 3.41). Results from the Arab American Eye Study suggest that the burden of cataract and diabetic retinopathy is significantly higher among Arab Americans in comparison to whites.
为了估计在阿拉伯裔美国人社区中白内障、糖尿病性视网膜病变、青光眼和黄斑变性的年龄和性别调整比例，这是一个明显研究不足的少数族裔，被归为白人。阿拉伯裔美国人眼部研究是一项涉及 10 年电子病历（2010 年 1 月 1 日至 2020 年 1 月 1 日）的多中心回顾性图表审查。研究样本包括 1390 名阿拉伯裔美国人和 4950 名 45 岁及以上的白人，总计 6340 名受试者。使用阿拉伯裔美国人姓名算法识别阿拉伯裔美国人。研究排除了种族变量不是白人或阿拉伯裔美国人或年龄在 45 岁以下的受试者。确定了白内障、糖尿病性视网膜病变、青光眼和黄斑变性的年龄和性别调整比例。使用 95%置信区间的比值比来检查种族/民族与眼部疾病之间的关联。在 6340 名参与者（4950 名白人，1390 名阿拉伯裔美国人）中，男性占 46.3%，中位年龄组为 55-64 岁。阿拉伯裔美国人白内障的年龄和性别调整比例较高（45.4%比 40.7%）、干性年龄相关性黄斑变性（10%比 8.9%）、青光眼（8%比 6%）和糖尿病性视网膜病变（11.7%比 4.2%）。完全调整的逻辑回归显示，阿拉伯裔美国人患白内障的可能性高 19%（比值比 1.19；95%置信区间 1.05，1.35），患糖尿病性视网膜病变的可能性高 272%（比值比 2.72；95%置信区间 2.17；3.41）。阿拉伯裔美国人眼部研究的结果表明，与白人相比，阿拉伯裔美国人白内障和糖尿病性视网膜病变的负担明显更高。
