Kini M M, Leibowitz H M, Colton T, Nickerson R J, Ganley J, Dawber T R
Am J Ophthalmol. 1978 Jan;85(1):28-34. doi: 10.1016/s0002-9394(14)76661-9.
Of the Framingham, Massachusetts Heart Study population, 2,675 individuals underwent an ophthalmologic evaluation that stressed detection of senile cataract, diabetic retinopathy, open-angle glaucoma, and senile macular degeneration. Those examined were 52 to 85 years old at the time this study was initiated. The prevalence rate of each of these ocular conditions increased with age. Prevalence of senile cataracts ranged from 4.6% for those between the ages of 52 to 64 years to 46% for those 75 to 85 years of age. Diabetic retinopathy was present in 2% of those between 52 and 64 years of age or older. Overall prevalence of senile macular degeneration was 9%, with a prevalence rate of 2% in our youngest age group and 28% in the oldest age group. Open-angle glaucoma had an overall prevalence of approximately 3%. This disease also showed a statistically significant (P less than .01) increase with age from 1.4% (52 to 64 years old) to 7.2% (75 to 85 years old).
在马萨诸塞州弗雷明汉心脏研究人群中,2675人接受了眼科评估,重点是检测老年性白内障、糖尿病视网膜病变、开角型青光眼和老年性黄斑变性。在本研究开始时,接受检查者年龄在52至85岁之间。这些眼部疾病的患病率均随年龄增长而升高。老年性白内障的患病率在52至64岁人群中为4.6%,在75至85岁人群中为46%。糖尿病视网膜病变在52岁及以上64岁以下人群中的患病率为2%。老年性黄斑变性的总体患病率为9%,在最年轻年龄组中为2%,在最年长年龄组中为28%。开角型青光眼的总体患病率约为3%。该疾病也随年龄增长呈现出统计学显著升高(P小于0.01),从1.4%(52至64岁)升至7.2%(75至85岁)。