Aggarwal P K, Kumar L, Garg S K, Mathur V S
Ann Allergy. 1986 Feb;56(2):177-82.
The antihistaminic, anticholinergic, antibradykinin, and/or antiprostaglandin activity of aqueous and the alcoholic leaf extracts of the plant Rumex nepalensis were tested on the prepared site on the back of rabbits, using a control and a test site. Aqueous extract was found to reduce the mean size of the wheal produced by histamine, acetylcholine, carbachol, and bradykinin. The alcoholic extract reduced the size of the wheal produced by histamine, acetylcholine and carbachol. The results indicate that Rumex nepalensis may have antihistaminic, anticholinergic, and/or antibradykinin activity.
在兔子背部的制备部位，利用一个对照部位和一个测试部位，对尼泊尔酸模植物水提取物和醇提取物的抗组胺、抗胆碱能、抗缓激肽和/或抗前列腺素活性进行了测试。结果发现，水提取物可减小由组胺、乙酰胆碱、卡巴胆碱和缓激肽产生的风团平均大小。醇提取物可减小由组胺、乙酰胆碱和卡巴胆碱产生的风团大小。结果表明，尼泊尔酸模可能具有抗组胺、抗胆碱能和/或抗缓激肽活性。
