Breast Cancer Radiation Therapy Unit, at Sheba Medical Center, Ramat Gan, Israel; Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel; GROW-School for Oncology and Developmental Biology (Maastro), Maastricht University, Maastricht, The Netherlands.
Department of Radiation Oncology, Dalhousie University, Halifax, Canada.
Radiother Oncol. 2021 Nov;164:115-121. doi: 10.1016/j.radonc.2021.09.012. Epub 2021 Sep 24.
Bolus serves as a tissue equivalent material that shifts the 95-100% isodose line towards the skin and subcutaneous tissue. The need for bolus for all breast cancer patients planned for postmastectomy radiation therapy (PMRT) has been questioned. The work was initiated by the faculty of the European SocieTy for Radiotherapy & Oncology (ESTRO) breast cancer courses and represents a multidisciplinary international breast cancer expert collaboration to optimize PMRT. Due to the lack of randomised trials evaluating the benefits of bolus, we designed a stepwise project to evaluate the existing evidence about the use of bolus in the setting of PMRT to achieve an international consensus for the indications of bolus in PMRT, based on the Delphi method.
组织等效物填充物可使 95-100%等剂量线向皮肤和皮下组织转移。目前对于所有计划接受乳腺癌根治术后放疗（PMRT）的患者是否需要使用填充物仍存在争议。这项工作是由欧洲放射肿瘤学会（ESTRO）乳腺癌课程的教师发起的，代表了一个多学科的国际乳腺癌专家合作，旨在优化 PMRT。由于缺乏随机试验来评估填充物的益处，我们设计了一个逐步项目来评估 PMRT 中使用填充物的现有证据，以基于德尔菲法达成关于 PMRT 中使用填充物的适应症的国际共识。
