Adlung J
Z Gastroenterol. 1978 Mar;16(3):179-87.
From various breath tests up to now mainly measurement of respiratory 14CO2 and hydrogen have attained clinical application. Breath tests are easily performable, without discomfort for patient or in investigator and do hardly require active support of the patient. On the other hand absorption tests, as 14C-tripalmitate- and 14C-lactose-breath test, are influenced by alterations of the metabolism in a considerable degree, and clinical significance and specificity of the 14C-cholylcycline-breath test remains questionable hitherto. Nevertheless, obtained values which are independent from metabolism, high sensitivity and lack of competitive methods are arguments for the 14C-cholylglycinebreth test for the diagnosis of bacterial overgrowth in the small bowel. Breath analysis of hydrogen seems to be a very sensitive and reliable method for detecting carbohydrate malabsorption, as lactose intolerance.
到目前为止,从各种呼气试验来看,主要是呼吸14CO2和氢气的测量已获得临床应用。呼气试验易于操作,对患者或检查者都没有不适,而且几乎不需要患者的主动配合。另一方面,吸收试验,如14C-三棕榈酸酯和14C-乳糖呼气试验,在很大程度上受代谢改变的影响,并且14C-胆酰环素呼气试验的临床意义和特异性迄今仍存在疑问。然而,独立于代谢的获得值、高灵敏度以及缺乏竞争性方法,是14C-甘氨胆酸呼气试验用于诊断小肠细菌过度生长的依据。氢气呼气分析似乎是检测碳水化合物吸收不良(如乳糖不耐受)的一种非常灵敏且可靠的方法。