Faculty of Chemistry, Northeast Normal University, Changchun 130024, P. R. China.
ACS Appl Mater Interfaces. 2021 Oct 6;13(39):47155-47162. doi: 10.1021/acsami.1c14231. Epub 2021 Sep 26.
The excellent adhesion of mussels under wet conditions has inspired the development of numerous catechol-based wet adhesives. Nevertheless, the performance of catechol-based wet adhesive suffers from the sensitivity toward temperature, pH, or oxidation stimuli. Therefore, it is of great significance to develop non-catechol-based wet adhesives to fully recapitulate nature's dynamic function. Herein, a novel type of non-catechol-based wet adhesive is reported, which is readily formed by self-assembly of commercially available branched polyethylenimine and phosphotungstic acid in aqueous solution through the combination of electrostatic interaction and hydrogen bonding. This wet adhesive shows reversible, tunable, and strong adhesion on diverse substrates and further exhibits high efficacy in promoting biological wound healing. During the healing of the wound, the as-prepared wet adhesive also possesses inherent antimicrobial properties, thus avoiding inflammations and infections due to microorganism accumulation.
在潮湿条件下，贻贝具有极好的附着力，这启发了人们开发出许多基于儿茶酚的湿胶。然而，基于儿茶酚的湿胶的性能受到温度、pH 值或氧化刺激的敏感性的影响。因此，开发非基于儿茶酚的湿胶来充分重现自然的动态功能具有重要意义。本文报道了一种新型的非基于儿茶酚的湿胶，它可通过在水溶液中自组装商业可得的支化聚乙烯亚胺和磷钨酸，通过静电相互作用和氢键的结合来轻易形成。这种湿胶在各种基质上表现出可重复、可调且强的附着力，并且在促进生物伤口愈合方面具有高效性。在伤口愈合过程中，所制备的湿胶还具有固有的抗菌性能，从而避免了因微生物积累而引起的炎症和感染。
