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原发性睾丸平滑肌肉瘤：一例报告

Primary Testis Leiomyosarcoma: A Case Report.

作者信息

Nazar Elham, Shabanzadeh Zohre, Ahmadi Amir, Rostami Niloofar

出版信息

Iran J Pathol. 2021 Fall;16(4):461-464. doi: 10.30699/ijp.2021.524644.2586. Epub 2021 Jul 6.

DOI:10.30699/ijp.2021.524644.2586
PMID:34567199
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8463765/
Abstract

Primary leiomyosarcoma in testis is an uncommon tumor with few cases reported. It generally develops after radiotherapy or long-term taking anabolic steroid medication. We report a 53-year-old male patient with primary testis leiomyosarcoma who presented with painless testicular enlargement without any known predisposing factors. Ultrasound revealed a large heterogeneous left testicular solid lesion. Alpha-fetoprotein (AFP) and beta-human chorionic gonadotrophin (beta-HCG) levels in serum were normal. Left radical orchidectomy following with histology assessment established a diagnosis of primary leiomyosarcoma of testis. No data of cancer metastasis was established. The patient didn't receive any adjuvant therapy. There wasn't any evidence of recurrence after 1 year follow-up. Leiomyosarcoma must be one of the differential diagnoses of seronegative tumors in testis. The motivation for this paper is the extreme infrequency of the situation and the differential diagnosis by all expansive inguinoscrotal tumors.

摘要

睾丸原发性平滑肌肉瘤是一种罕见肿瘤，报道的病例很少。它通常在放疗后或长期服用合成代谢类固醇药物后发生。我们报告一例53岁男性原发性睾丸平滑肌肉瘤患者，其表现为无痛性睾丸肿大，无任何已知的诱发因素。超声检查显示左侧睾丸有一个大的不均匀实性病变。血清中甲胎蛋白（AFP）和β-人绒毛膜促性腺激素（β-HCG）水平正常。经组织学评估后行左侧根治性睾丸切除术，确诊为睾丸原发性平滑肌肉瘤。未发现癌症转移数据。该患者未接受任何辅助治疗。随访1年后未发现复发迹象。平滑肌肉瘤必须是睾丸血清学阴性肿瘤的鉴别诊断之一。本文的目的是鉴于这种情况极为罕见以及对所有扩展性腹股沟阴囊肿瘤进行鉴别诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75bf/8463765/0657a6393073/ijp-16-461-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75bf/8463765/8ffb76456d31/ijp-16-461-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75bf/8463765/41fb0f0dc943/ijp-16-461-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75bf/8463765/5f0c455991d0/ijp-16-461-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75bf/8463765/0657a6393073/ijp-16-461-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75bf/8463765/8ffb76456d31/ijp-16-461-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75bf/8463765/41fb0f0dc943/ijp-16-461-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75bf/8463765/5f0c455991d0/ijp-16-461-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75bf/8463765/0657a6393073/ijp-16-461-g004.jpg

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本文引用的文献

1
Primary high grade testicular leiomyosarcoma: A rare malignancy in a young male.原发性高级别睾丸平滑肌肉瘤：年轻男性中的一种罕见恶性肿瘤。
Turk J Urol. 2018 Mar;44(2):178-181. doi: 10.5152/tud.2017.15821. Epub 2017 Dec 11.
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High grade leiomyosarcoma of the testes.睾丸高级别平滑肌肉瘤
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Primary testicular leiomyosarcoma.
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Testicular leiomyosarcoma with metastasis.伴有转移的睾丸平滑肌肉瘤
Indian J Urol. 2011 Apr;27(2):278-9. doi: 10.4103/0970-1591.82854.
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Primary leiomyosarcoma of the testis. A case report.睾丸原发性平滑肌肉瘤。一例报告。
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Leiomyosarcoma of the spermatic cord: case report and literature review.精索平滑肌肉瘤：病例报告与文献综述
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