10033London Regional Cancer Centre & London Health Sciences Centre, London, ON, Canada.
8430University of Waterloo School of Pharmacy, Kitchener, ON, Canada.
J Oncol Pharm Pract. 2022 Dec;28(8):1763-1770. doi: 10.1177/10781552211041680. Epub 2021 Sep 27.
A prospective open-label randomized controlled trial to assess the role of a picture-based medication calendar on adherence to antiemetic regimens for adult patients receiving chemotherapy and assess the effect on other medication taking behaviors as well as patient satisfaction with the tool.
Participants were randomly assigned 1:1 to routine care with or without calendar.
Adherence, stratified by education (university or postgraduate, = 0.09; grade school, high school or college = 0.32), was non-significantly different between study arms. At least 70% of intervention arm participants moderately or completely agreed that the calendar helped with medication taking behaviors. There was no statistical difference between study arms for perceived regimen complexity ( = 0.16). Medication Use and Self Efficacy score (adjusted for age) used to assess perceived self-efficacy with medication taking behaviors were not statistically significant between study arms ( = 0.09).
The picture-based medication calendar did not statistically affect adherence to scheduled antiemetics among outpatients receiving chemotherapy for solid organ tumor origins. However, participants indicated that the calendar was effective for keeping track of medications, had an easy-to-understand layout, and provided help around when and how to take medications related to the oncology regimen.
一项前瞻性、开放标签、随机对照试验，旨在评估基于图片的药物日历对接受化疗的成年患者抗恶心药物治疗方案依从性的作用，并评估其对其他药物使用行为以及患者对该工具的满意度的影响。
参与者按 1:1 随机分配至常规护理加或不加日历组。
按教育程度分层（大学或研究生学历=0.09；小学、中学或大专学历=0.32），研究组间的依从性无显著差异。干预组至少 70%的参与者表示，日历在一定程度上或完全有助于他们的服药行为。研究组间对治疗方案复杂性的感知无统计学差异（=0.16）。用于评估对服药行为的自我效能感的药物使用和自我效能评分（根据年龄进行调整）在研究组间无统计学差异（=0.09）。
对于接受化疗的实体肿瘤起源的门诊患者，基于图片的药物日历并未在统计学上影响计划中的抗恶心药物的依从性。然而，参与者表示，该日历在跟踪药物方面非常有效，布局易于理解，并提供了有关何时以及如何服用与肿瘤治疗方案相关药物的帮助。
