Chuang Yu-Han, Tan Chun-Hsiang, Su Hui-Chen, Chien Chung-Yao, Sung Pi-Shan, Lee Tsung-Lin, Yu Rwei-Ling
Institute of Behavioral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Department of Neurology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
J Parkinsons Dis. 2022;12(1):185-197. doi: 10.3233/JPD-212830.
Hypomimia is a clinical feature of Parkinson's disease (PD). Based on the embodied simulation theory, the impairment of facial mimicry may worsen facial emotion recognition; however, the empirical results are inconclusive.
We aimed to explore the worsening of emotion recognition by hypomimia. We further explored the relationship between the hypomimia, emotion recognition, and social functioning.
A total of 114 participants were recruited. The patients with PD and normal controls (NCs) were matched for demographic characteristics. All the participants completed the Mini-Mental State Examination and the Chinese Multi-modalities Emotion Recognition Test. In addition to the above tests, the patients were assessed with the Movement Disorder Society-Unified Parkinson's Disease Rating Scale and Parkinson's Disease Social Functioning Scale (PDSFS).
Patients with PD with hypomimia had worse recognition of disgust than NCs (p = 0.018). The severity of hypomimia was predictive of the recognition of disgust (β= -0.275, p = 0.028). Facial emotion recognition was predictive of the PDSFS score of PD patients (β= 0.433, p = 0.001). We also found that recognizing disgust could mediate the relationship between hypomimia and the PDSFS score (β= 0.264, p = 0.045).
Patients with hypomimia had the worst disgust facial recognition. Hypomimia may affect the social function of PD patients, which is related to recognizing the expression of disgust. Emotion recognition training may improve the social function of patients with PD.
面无表情是帕金森病（PD）的临床特征之一。基于具身模拟理论，面部模仿功能受损可能会使面部情绪识别能力恶化；然而，实证结果尚无定论。
我们旨在探究面无表情对面部情绪识别能力的恶化影响。我们进一步探究了面无表情、情绪识别和社会功能之间的关系。
共招募了114名参与者。帕金森病患者和正常对照组（NCs）在人口统计学特征上进行了匹配。所有参与者均完成了简易精神状态检查表和中国多模态情绪识别测试。除上述测试外，还使用运动障碍协会统一帕金森病评定量表和帕金森病社会功能量表（PDSFS）对患者进行评估。
面无表情的帕金森病患者对厌恶情绪的识别能力比正常对照组差（p = 0.018）。面无表情的严重程度可预测对厌恶情绪的识别能力（β = -0.275，p = 0.028）。面部情绪识别能力可预测帕金森病患者的PDSFS评分（β = 0.433，p = 0.001）。我们还发现，对厌恶情绪的识别能力可介导面无表情与PDSFS评分之间的关系（β = 0.264，p = 0.045）。
面无表情的患者对厌恶情绪的面部识别能力最差。面无表情可能会影响帕金森病患者的社会功能，这与对厌恶情绪表达的识别有关。情绪识别训练可能会改善帕金森病患者的社会功能。
