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两种局部用药对大鼠颈动脉显微缝合后血栓形成作用的双盲研究(作者译)

[Double blind study of the action of two topic drugs on the thrombosis of the carotid artery of rats after microsuture (author's transl)].

作者信息

Vannineuse A

出版信息

Acta Chir Belg. 1978 Jan-Feb;77(1):5-8.

PMID:345701
Abstract

The action of 2 topic agents on the thrombosis of the carotid artery after microsuture was studied in rats. These drugs were magnesium sulfate whose antithrombotic effect has been demonstrated in vitro, and Ringer lactate considered inactive on coagulation. Twenty-two randomized rats underwent an end-to-end microsuture of the primitive carotid artery, the solutions being used to wash the lumen of the vessel and to irrigate the operative field. Arterial patency was controlled after one hour and after 10 days. No statistically significant difference was found between the two series.

摘要

在大鼠身上研究了两种局部用药对显微缝合后颈动脉血栓形成的作用。这些药物是已在体外证明具有抗血栓作用的硫酸镁,以及被认为对凝血无活性的乳酸林格液。22只随机分组的大鼠接受了原始颈动脉的端端显微缝合,使用这些溶液冲洗血管腔并冲洗手术区域。分别在1小时和10天后检查动脉通畅情况。两个组之间未发现统计学上的显著差异。

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