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[实验性动脉显微缝合术。使用锝99标记肝素评估血栓形成风险]

[Experimental arterial microsutures. Evaluation of the risks of thrombosis using technetium 99-labeled heparin].

作者信息

Berthelot J L, Colas-Linhart N, Petiet A, Bok B

出版信息

Neurochirurgie. 1986;32(6):501-6.

PMID:3547158
Abstract

Following demonstration of a method of assay of circulation heparin by measurement of radioactivity after labelling with 99 m technetium, the technique was used to study effects of arterial microsuture on metabolism of heparin injected postoperatively. Results of a study involving rat aorta showed that local binding was maximum during the first half-hour and that abnormal consumption of heparin continued during the 6 hours following operation. These finding suggest that a risk of thrombosis probably persists throughout this postoperative period.

摘要

在用99m锝标记后通过测量放射性来测定循环肝素的方法得到证实后,该技术被用于研究动脉显微缝合对术后注射肝素代谢的影响。一项涉及大鼠主动脉的研究结果表明,局部结合在最初半小时达到最大,并且肝素的异常消耗在术后6小时内持续存在。这些发现表明,在整个术后期间可能持续存在血栓形成的风险。

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