Berthelot J L, Colas-Linhart N, Petiet A, Bok B
Neurochirurgie. 1986;32(6):501-6.
Following demonstration of a method of assay of circulation heparin by measurement of radioactivity after labelling with 99 m technetium, the technique was used to study effects of arterial microsuture on metabolism of heparin injected postoperatively. Results of a study involving rat aorta showed that local binding was maximum during the first half-hour and that abnormal consumption of heparin continued during the 6 hours following operation. These finding suggest that a risk of thrombosis probably persists throughout this postoperative period.
在用99m锝标记后通过测量放射性来测定循环肝素的方法得到证实后,该技术被用于研究动脉显微缝合对术后注射肝素代谢的影响。一项涉及大鼠主动脉的研究结果表明,局部结合在最初半小时达到最大,并且肝素的异常消耗在术后6小时内持续存在。这些发现表明,在整个术后期间可能持续存在血栓形成的风险。