Curzon M E, Richardson D S, Featherstone J D
J Dent Res. 1986 Mar;65(3):421-3. doi: 10.1177/00220345860650030901.
The effect of lithium (Li) in drinking water on caries prevalence in seven Texas towns was investigated. Children (life-long residents) aged 12-14 years were examined for caries prevalence, as DMFS, in towns with drinking water Li concentrations ranging from 0.0 to 165 micrograms/L and fluoride (F) concentrations ranging from 0.20 to 1.94 mg/L. A significant negative relationship was found between F in drinking water and DMFS. When corrected for the F contribution, Li in water supplies showed a positive correlation with DMFS.