Pulmonology Department, Centro Hospitalar e Universitário de São João, Porto, Portugal.
Pulmonology Department, Centro Hospitalar e Universitário de São João, Porto, Portugal; Faculty of Medicine, University of Porto, Porto, Portugal.
Pulm Pharmacol Ther. 2021 Dec;71:102078. doi: 10.1016/j.pupt.2021.102078. Epub 2021 Sep 24.
Actinomycosis is a rare chronic infection triggered by species of Actinomyces. Although thoracic involvement represents about 15% of human actinomycosis, its true incidence may be underestimated, not only because of its challenging diagnosis, but also because it can be treated unintentionally with antibiotics for other diseases. In this sense, this work aims at providing an up-to-date literature review on thoracic actinomycoses, with particular emphasis on presentation, diagnostic and therapeutic approaches, also paving upcoming clinical interventions from findings obtained of a presentation of a case series. Data discussed here clearly denote the rarity, non-specificity and heterogeneity of clinical presentations of the disease, reinforcing the need for individualized therapeutic approaches.
放线菌病是由放线菌属物种引发的罕见慢性感染。尽管胸部受累约占人类放线菌病的 15%，但其真实发病率可能被低估了，这不仅是因为其诊断具有挑战性，还因为它可能会被无意间用抗生素治疗其他疾病。从这个意义上说，本工作旨在提供有关胸放线菌病的最新文献综述，特别强调其临床表现、诊断和治疗方法，并根据一系列病例报告的研究结果，为即将开展的临床干预措施提供依据。这里讨论的数据清楚地表明了该疾病临床表现的稀有性、非特异性和异质性，这进一步强调了个体化治疗方法的必要性。
