Huang Lin-Yi, Chen Wan-Ju, Yang Yung-Ning, Wu Chien-Yi, Wu Pei-Ling, Tey Shu-Leei, Yang San-Nan, Liu Hsien-Kuan
Department of Pediatrics, E-DA Hospital, Kaohsiung 82445, Taiwan.
College of Medicine, I-Shou University, Kaohsiung 82445, Taiwan.
Children (Basel). 2021 Sep 1;8(9):771. doi: 10.3390/children8090771.
Sudden infant death syndrome (SIDS) has always been a regrettable issue for families. After sleeping in the supine position was proposed, the incidence of SIDS declined dramatically worldwide. However, SIDS still accounts for the top 10 causes of infant deaths in Taiwan. Recognizing the risk factors and attempting to minimize these cases are imperative. We obtained information on cases with SIDS from the National Health Insurance Research Database in Taiwan and interconnected it with the Taiwan Maternal and Child Health Database to acquire infant-maternal basal characteristics between 2004 and 2017. The SIDS subjects were matched 1:10 considering gestational age to normal infants. After case selection, a total of 953 SIDS cases were included. Compared with healthy infants, SIDS infants had younger parents, lower birth weight, and lower Apgar scores. After adjusting for potential confounders, infants with mothers aged <20 years had 2.81 times higher risk of SIDS. Moreover, infants in the non-eastern region had a significantly lower risk of SIDS than those in the eastern region. We concluded that infants of young mothers (especially maternal age <20 years) and infants in the eastern region of Taiwan had a higher risk of SIDS than their counterparts.
婴儿猝死综合征（SIDS）一直是令家庭遗憾的问题。自从提出仰卧睡眠姿势后，全球范围内SIDS的发病率大幅下降。然而，SIDS仍是台湾婴儿死亡的前十大原因之一。认识到风险因素并试图减少这些病例势在必行。我们从台湾国民健康保险研究数据库中获取了SIDS病例的信息，并将其与台湾妇幼健康数据库相连接，以获取2004年至2017年间婴儿和母亲的基本特征。考虑到胎龄，将SIDS受试者与正常婴儿按1:10进行匹配。经过病例筛选，共纳入953例SIDS病例。与健康婴儿相比，SIDS婴儿的父母年龄较小、出生体重较低且阿氏评分较低。在对潜在混杂因素进行调整后，母亲年龄＜20岁的婴儿发生SIDS的风险高出2.81倍。此外，非东部地区的婴儿发生SIDS的风险明显低于东部地区。我们得出结论，年轻母亲（尤其是母亲年龄＜20岁）的婴儿以及台湾东部地区的婴儿发生SIDS的风险高于其他婴儿。
