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社区中的抗生素使用及其认知:孟加拉国新冠疫情期间的一项手机调查

Antibiotics Use and Its Knowledge in the Community: A Mobile Phone Survey during the COVID-19 Pandemic in Bangladesh.

作者信息

Akhtar Zubair, Mah-E-Muneer Syeda, Rashid Md Mahbubur, Ahmed Md Shakil, Islam Md Ariful, Chowdhury Sukanta, Khan Zobaid, Hassan Md Zakiul, Islam Khaleda, Parveen Shahana, Debnath Nitish, Rahman Mahmudur, Chowdhury Fahmida

机构信息

Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, Bangladesh.

Fleming Fund Country Grant to Bangladesh, DAI Global, LLC, House 3, First Floor, Road 23B, Gulshan 1, Dhaka 1212, Bangladesh.

出版信息

Antibiotics (Basel). 2021 Aug 29;10(9):1052. doi: 10.3390/antibiotics10091052.

Abstract

The general population has been excessively using antibiotics during the COVID-19 pandemic. Therefore, the use of antibiotics for any reported illnesses in the preceding four weeks and knowledge of antibiotics among the general population in the community were assessed for possible interventions. A mobile phone survey among a general population across eight administrative divisions of Bangladesh was conducted during January-March 2021. Reported illness episodes irrespective of COVID-19 in the preceding four weeks of the interview, use of antibiotics for the illnesses, and knowledge on antibiotics among the general population were recorded. Descriptive analyses were performed. We randomly interviewed 1854 participants, with a mean age of 28.5 years (range: 18-75 years); 60.6% were male. Among all participants, 86.3% (95% CI: 84.7-87.8) heard names of antibiotics, but only 12.1% reported unspecified harmful effects, and 3.5% reported antimicrobial resistance when antibiotics were taken without a physician's prescription. Among 257 (13.9%) participants, who consumed medicines for their recent illness episode, 32.7% (95% CI: 27.2-38.6) reported using antibiotics. Of those who could recall the names of antibiotics prescribed (n = 36), the most frequently used was azithromycin (22.2%) followed by cefixime (11.1%) and ciprofloxacin (5.6%). Our findings show an increased antibiotic use for illnesses reported in the preceding four weeks and an elevated knowledge at the community level during the COVID-19 pandemic compared with the pre-pandemic period.

摘要

在新冠疫情期间,普通民众过度使用了抗生素。因此,对前四周内报告的任何疾病的抗生素使用情况以及社区普通民众对抗生素的了解进行了评估,以确定可能的干预措施。2021年1月至3月期间,在孟加拉国八个行政区对普通民众进行了一项手机调查。记录了访谈前四周内不论是否感染新冠的报告疾病发作情况、针对这些疾病使用抗生素的情况以及普通民众对抗生素的了解情况。进行了描述性分析。我们随机采访了1854名参与者,平均年龄为28.5岁(范围:18至75岁);60.6%为男性。在所有参与者中,86.3%(95%置信区间:84.7 - 87.8)听说过抗生素的名称,但只有12.1%报告了未明确的有害影响,3.5%报告在无医生处方情况下服用抗生素会产生抗微生物耐药性。在257名(13.9%)近期因病服药的参与者中,32.7%(95%置信区间:27.2 - 38.6)报告使用了抗生素。在那些能够回忆起所开抗生素名称的人(n = 36)中,最常用的是阿奇霉素(22.2%),其次是头孢克肟(11.1%)和环丙沙星(5.6%)。我们的研究结果表明,与疫情前相比,在新冠疫情期间,前四周报告疾病的抗生素使用有所增加,社区层面的了解也有所提高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4275/8469517/369c0baa7c84/antibiotics-10-01052-g001.jpg

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