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缅甸公众对抗生素和抗生素耐药性的知识、实践和认知:首次全国手机面板调查。

Public knowledge, practices, and awareness of antibiotics and antibiotic resistance in Myanmar: The first national mobile phone panel survey.

机构信息

Advisor for Infectious Disease Control and Laboratory Services, Japan International Cooperation Agency (JICA), Yangon, Myanmar.

Bureau of International Health Cooperation, National Center for Global Health and Medicine (NCGM), Tokyo, Japan.

出版信息

PLoS One. 2022 Aug 18;17(8):e0273380. doi: 10.1371/journal.pone.0273380. eCollection 2022.

Abstract

In 2017, the Myanmar National Action Plan for Containment of Antimicrobial Resistance (AMR) (2017-2022) was endorsed by the Ministry of Health and Sports, Myanmar; one of its objectives was to increase public awareness of AMR to accelerate appropriate antibiotic use. This survey aimed to assess the public knowledge, practices and awareness concerning antibiotics and AMR awareness among adults in Myanmar. We conducted a nationwide cross-sectional mobile phone panel survey in January and February 2020. Participants were randomly selected from the mobile phone panel in each of three groups stratified by gender, age group, and residential area urbanity; they were interviewed using a structured questionnaire. Collected data were weighted based on the population of each stratum from the latest national census and analyzed using descriptive and inferential statistics. Two thousand and forty-five adults from 12 regions and states participated in this survey. Overall, 89.5% of participants had heard about antibiotics; however, only 0.9% provided correct answers to all five questions about antibiotics, whereas 9.7% provided all incorrect answers. More than half of participants (58.5%) purchased antibiotics without a prescription, mainly from medical stores or pharmacies (87.9%); this was more frequent in age group (18-29 years) and those in rural areas (p = 0.004 and p < 0.001, respectively). Only 56.3% were aware of antibiotic resistance and received their information from medical professionals (46.3%), family members or friends (38.9%), or the media (26.1%). Less than half (42.4%) knew that antibiotics were used in farm animals. Most did not know that using antibiotics in farm animals could develop resistance (73.2%) and is banned for the purposes of growth stimulation (64.1%). This survey identifies considerable gaps in the knowledge, practices, and awareness about antibiotics among the general population in Myanmar. Continuous public education and awareness campaigns must be urgently conducted to fulfill these gaps, which would aid in promoting antibiotic stewardship, leading to combating AMR in Myanmar.

摘要

2017 年,缅甸卫生体育部批准了《缅甸遏制抗微生物药物耐药性国家行动计划(2017-2022 年)》,其目标之一是提高公众对抗微生物药物耐药性的认识,以加速合理使用抗生素。本调查旨在评估缅甸成年人对抗生素和抗微生物药物耐药性的知识、实践和意识。我们于 2020 年 1 月和 2 月进行了一项全国性的手机面板横断面调查。参与者是从每个按性别、年龄组和居住地区城市化程度分层的手机面板中随机选择的;他们使用结构化问卷接受了采访。根据最新全国人口普查,对收集到的数据进行了基于每个阶层人口的加权处理,并使用描述性和推断性统计方法进行了分析。来自 12 个地区和邦的 2045 名成年人参加了这项调查。总体而言,89.5%的参与者听说过抗生素;然而,只有 0.9%的人能正确回答关于抗生素的五个问题,而 9.7%的人给出了所有错误答案。超过一半的参与者(58.5%)未经处方购买抗生素,主要从药店或药房购买(87.9%);年龄组(18-29 岁)和农村地区的这一比例更高(p=0.004 和 p<0.001)。只有 56.3%的人意识到抗生素耐药性,并从医务人员(46.3%)、家人或朋友(38.9%)或媒体(26.1%)获得信息。不到一半(42.4%)的人知道抗生素在农场动物中使用。大多数人不知道在农场动物中使用抗生素会产生耐药性(73.2%),并且禁止用于促进生长(64.1%)。这项调查确定了缅甸普通民众在抗生素知识、实践和意识方面存在相当大的差距。必须紧急开展持续的公众教育和宣传活动,以填补这些空白,这将有助于促进抗生素管理,从而对抗缅甸的抗微生物药物耐药性。

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