Bramsen T, Corydon L, Ehlers N
Acta Ophthalmol (Copenh). 1978 Feb;56(1):121-6. doi: 10.1111/j.1755-3768.1978.tb00474.x.
A double-blind study of the influence of systemic tranexamic acid on the central corneal thickness after cataract extraction was performed in 17 pairs of patients. Apart from the cataract, no were present. A sequential statistics was used to show that the increase in central corneal thickness after operation was significantly less in the tranexamic acid treated group than in the placebo group. There was no significant difference in intraocular pressure between the tranexamic acid and the placebo treated group. The possible influence of tranexamic acid on the thickness controlling mechanism of the cornea is discussed, and studies concerning the fibrinolytic system, the complement system and the aqueous humour amino acid treated patients are mentioned.
对17对患者进行了一项关于全身应用氨甲环酸对白内障摘除术后中央角膜厚度影响的双盲研究。除白内障外，无其他疾病。采用序贯统计显示，氨甲环酸治疗组术后中央角膜厚度的增加明显少于安慰剂组。氨甲环酸治疗组与安慰剂治疗组的眼压无显著差异。讨论了氨甲环酸对角膜厚度控制机制的可能影响，并提及了关于纤维蛋白溶解系统、补体系统和房水氨基酸治疗患者的研究。
