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氨甲环酸与迟发性前房积血。白内障手术的一项双盲研究。

Tranexamic acid (AMCA) and late hyphaema. A double blind study in cataract surgery.

作者信息

Jerndal T, Frisén M

出版信息

Acta Ophthalmol (Copenh). 1976 Aug;54(4):417-29. doi: 10.1111/j.1755-3768.1976.tb01273.x.

Abstract

A double blind study of the effect of tranexamic acid (AMCA) on late hyphaema after cataract surgery is reported. A total of 244 patients were included in the study after strict selection. It was shown that the incidence of late hyphaema in the treated group was significantly lower at the 5% level than that in the placebo group. The conclusion is made that the fibrinolytic inhibitor tranexamic acid can be used therapeutically or prophylactically to decrease the risk for re-bleeding after ocular surgery.

摘要

本文报道了一项关于氨甲环酸(AMCA)对白内障手术后迟发性前房积血影响的双盲研究。经过严格筛选,共有244例患者纳入本研究。结果显示,治疗组迟发性前房积血的发生率在5%水平上显著低于安慰剂组。得出的结论是,纤溶抑制剂氨甲环酸可用于治疗或预防,以降低眼科手术后再出血的风险。

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