Conselleria de Sanitat i Salut Pública, Generalitat Valenciana, 46010 Valencia, Spain.
School of Medicine and Health Sciences, Valencia Catholic University, 46001 Valencia, Spain.
Int J Environ Res Public Health. 2021 Sep 18;18(18):9853. doi: 10.3390/ijerph18189853.
This study analyzed the prevalence, costs and economic impact of chronic kidney disease CKD in patients with T2D in a Spanish Health District using real-world data. Observational cross-sectional study in adult patients with T2D was through data extracted from the information systems of the Valencia Clínico-La Malvarrosa Health District in the year 2015. Patients were stratified with the KDIGO classification for CKD. Additionally, patients were assigned to Clinical Risk Groups (CRGs) according to multimorbidity. Direct costs of primary and specialized care, and medication were estimated. The prevalence of T2D in the database population ( = 28,345) was 10.8% (mean age (SD) = 67.8 years (13.9); 51.5% male). Up to 14.935 patients (52.6%) had data on kidney function. According to the KDIGO classification, 66.2% of the patients were at low risk of CKD, 20.6% at moderately increased risk, 7.9% at high risk, and 5.2% at very high risk. The average healthcare costs associated with these four risk groups were EUR 3437, EUR 4936, EUR 5899 and EUR 7389, respectively. The large number of T2D patients with CKD in the early stages of the disease generated a significant increase in direct healthcare costs. The economic impact could be mitigated by early and comprehensive therapeutic approaches.
本研究使用真实世界数据分析了西班牙某卫生区 2 型糖尿病（T2D）患者慢性肾脏病（CKD）的患病率、成本和经济影响。在 2015 年，通过从瓦伦西亚临床-拉马尔瓦罗萨卫生区的信息系统中提取的数据，对成年 T2D 患者进行了横断面观察性研究。患者按照 CKD 的 KDIGO 分类进行分层。此外，根据合并症将患者分为临床风险组（CRG）。估计了初级和专科护理以及药物治疗的直接费用。数据库人群中 T2D 的患病率（n=28345）为 10.8%（平均年龄（标准差）为 67.8 岁（13.9）；51.5%为男性）。多达 14935 名患者（52.6%）有肾功能数据。根据 KDIGO 分类，66.2%的患者 CKD 风险较低，20.6%风险中度增加，7.9%风险较高，5.2%风险极高。这四个风险组的平均医疗保健费用分别为 3437 欧元、4936 欧元、5899 欧元和 7389 欧元。大量处于疾病早期阶段的 T2D 合并 CKD 患者导致直接医疗保健费用显著增加。通过早期和全面的治疗方法可以减轻经济影响。
