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血管痉挛性心绞痛长期预后因素的当前证据

Current Evidence on Long-Term Prognostic Factors in Vasospastic Angina.

作者信息

Kim Hack-Lyoung, Jo Sang-Ho

机构信息

Division of Cardiology, Department of Internal Medicine, Boramae Medical Center, National University College of Medicine, Seoul 07061, Korea.

Division of Cardiology, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Anyang 14068, Korea.

出版信息

J Clin Med. 2021 Sep 21;10(18):4270. doi: 10.3390/jcm10184270.

Abstract

Vasospastic angina (VSA) is characterized by a reversible spasm of the coronary arteries and is more prevalent in Asians. Vasodilators, such as calcium channel blockers, are effective in relieving coronary spasms and preventing clinical events. Therefore, the prognosis of VSA is generally known to be better than for significant organic stenosis caused by atherosclerosis. However, coronary vasospasm is sometimes associated with fatal complications such as sudden death, ventricular arrhythmia, and myocardial infarction. Thus, it is very important to identify and actively treat high-risk patients to prevent VSA complications. Here, we will review clinical factors associated with long-term prognosis in patients with VSA.

摘要

变异性心绞痛(VSA)的特征是冠状动脉可逆性痉挛,在亚洲人中更为常见。血管扩张剂,如钙通道阻滞剂,可有效缓解冠状动脉痉挛并预防临床事件。因此,一般认为VSA的预后优于动脉粥样硬化引起的严重器质性狭窄。然而,冠状动脉痉挛有时会伴有致命并发症,如猝死、室性心律失常和心肌梗死。因此,识别并积极治疗高危患者以预防VSA并发症非常重要。在此,我们将回顾与VSA患者长期预后相关的临床因素。

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