Anaissie E, Kantarjian H, Jones P, Barlogie B, Luna M, Lopez-Berestein G, Bodey G P
Cancer. 1986 Jun 1;57(11):2141-5. doi: 10.1002/1097-0142(19860601)57:11<2141::aid-cncr2820571110>3.0.co;2-n.
Two cases of disseminated fungal infection due to Fusarium species, that occurred during a 4-month period, are reported. Both patients had a myeloproliferative disorder for which they had received intensive cytotoxic and immunosuppressive therapy, and both died despite treatment with amphotericin B. This report and review of the recent literature suggest that Fusarium is emerging as a newly recognized fungal pathogen in immunosuppressed patients.
报告了在4个月期间发生的两例由镰刀菌属引起的播散性真菌感染病例。两名患者均患有骨髓增殖性疾病,并接受了强化细胞毒性和免疫抑制治疗,尽管接受了两性霉素B治疗,但两人均死亡。本报告及对近期文献的综述表明,镰刀菌正在成为免疫抑制患者中新发现的真菌病原体。