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急性白血病患者播散性镰刀菌感染伴皮肤定位,经伏立康唑和两性霉素B脂质体复合物治疗取得成功结果。

Successful outcome of disseminated Fusarium infection with skin localization treated with voriconazole and amphotericin B-lipid complex in a patient with acute leukemia.

作者信息

Durand-Joly Isabelle, Alfandari Serge, Benchikh Zinnédine, Rodrigue Marion, Espinel-Ingroff Ana, Catteau Benoit, Cordevant Christophe, Camus Daniel, Dei-Cas Eduardo, Bauters Francis, Delhaes Laurence, De Botton Stéphane

机构信息

Parasitologie-Mycologie, Faculté de Médecine, CHRU de Lille, Lille, France.

出版信息

J Clin Microbiol. 2003 Oct;41(10):4898-900. doi: 10.1128/JCM.41.10.4898-4900.2003.

Abstract

A disseminated Fusarium oxysporum infection with skin localization was diagnosed in a woman with a relapse of B-acute leukemia during induction chemotherapy. The infection was refractory to amphotericin B-lipid complex alone but responded successfully when voriconazole was added.

摘要

一名患有B型急性白血病且在诱导化疗期间复发的女性被诊断为播散性尖孢镰刀菌感染伴皮肤定位。单独使用两性霉素B脂质体复合物治疗该感染无效,但添加伏立康唑后取得了成功疗效。

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