Furlow L T, Block A J, Williams W N
Cleft Palate J. 1986 Apr;23(2):153-8.
From 1967 to 1974 a clinical trial of Teflon injection into the posterior pharyngeal wall for correction of velopharyngeal incompetence (VPI) was conducted in thirty-six patients. Six years after Teflon injection, one of the patients reported the onset of severe snoring punctuated by silences when he seemed not to be breathing, daytime hypersomnolence, and tiredness severe enough to interfere with work and studies. The diagnosis of obstructive sleep apnea (OSA) was confirmed by polysomnographic sleep monitoring, and the dynamics of the obstruction elucidated by cinefluoroscopy performed with the patient asleep. Resection of the lower 3/4 of the Teflon pad, leaving the upper rim to avoid recurrence of his VPI, has eliminated the symptoms of OSA and produced an improvement in his polysomnographic findings.
1967年至1974年，对36例患者进行了一项临床试验，向咽后壁注射聚四氟乙烯以纠正腭咽闭合不全（VPI）。聚四氟乙烯注射6年后，其中一名患者报告出现严重打鼾，伴有呼吸暂停时的沉默，白天过度嗜睡，以及严重到足以干扰工作和学习的疲劳。通过多导睡眠监测确诊为阻塞性睡眠呼吸暂停（OSA），并在患者睡眠时通过荧光透视确定阻塞的动态情况。切除聚四氟乙烯垫的下3/4，保留上缘以避免VPI复发，消除了OSA的症状，并改善了多导睡眠监测结果。
