Chandan S N, Shetty Sahith Kumar, Deepa B V
Department of Oral and Maxillofacial Surgery, JSS Dental College and Hospital, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India.
Contemp Clin Dent. 2020 Apr-Jun;11(2):195-198. doi: 10.4103/ccd.ccd_380_19. Epub 2020 Aug 7.
Primary malignant melanoma of oral mucosa is a rare and aggressive tumor. It is usually seen in the 5 and 6 decades of life. Its mainstay of treatment is surgery. It has a very poor prognosis, which is attributed to its late detection and distant metastasis. Dentists are often the first clinicians to come across these lesions and need to be able to identify them at the earliest for a better prognosis. In this article, we present two cases of extensive primary malignant melanoma of the oral cavity. Clinically, both the cases had a similar appearance of grayish-black pigmented nodular swelling on the buccal aspect and grayish-black discoloration on the palatal aspect. There were no significant radiological changes in both cases, indicating the superficial spread of the lesion. A positron emission tomography scan was performed in the second patient, which did not show any distant metastasis. Surgery was advised as a treatment for both the patients.
口腔黏膜原发性恶性黑色素瘤是一种罕见且侵袭性强的肿瘤。它通常在50和60岁时出现。其主要治疗方法是手术。它的预后非常差，这归因于其发现较晚和远处转移。牙医常常是最早遇到这些病变的临床医生，需要能够尽早识别它们以获得更好的预后。在本文中，我们展示了两例广泛的口腔原发性恶性黑色素瘤病例。临床上，两例病例在颊侧均有类似的灰黑色色素沉着结节状肿胀外观，在腭侧有灰黑色变色。两例病例均无明显的影像学改变，表明病变为浅表扩散。对第二例患者进行了正电子发射断层扫描，未显示任何远处转移。建议对两名患者均进行手术治疗。
