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HBV 的治疗方法:未来展望。

Treatments for HBV: A Glimpse into the Future.

机构信息

Department of Medical and Surgical Sciences, Division of Internal Medicine, Maternal-Infantile and Adult, University of Modena and Reggio Emilia, 41126 Modena, Italy.

Postgraduate School of Allergy and Clinical Immunology, University of Modena and Reggio Emilia, 41126 Modena, Italy.

出版信息

Viruses. 2021 Sep 4;13(9):1767. doi: 10.3390/v13091767.

DOI:10.3390/v13091767
PMID:34578347
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8473442/
Abstract

The hepatitis B virus is responsible for most of the chronic liver disease and liver cancer worldwide. As actual therapeutic strategies have had little success in eradicating the virus from hepatocytes, and as lifelong treatment is often required, new drugs targeting the various phases of the hepatitis B virus (HBV) lifecycle are currently under investigation. In this review, we provide an overview of potential future treatments for HBV.

摘要

乙型肝炎病毒是全球大多数慢性肝病和肝癌的罪魁祸首。由于实际的治疗策略在从肝细胞中根除病毒方面收效甚微,而且通常需要终身治疗,因此目前正在研究针对乙型肝炎病毒 (HBV) 生命周期各个阶段的新药。在这篇综述中,我们概述了 HBV 的潜在未来治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90ca/8473442/0da36ba26b97/viruses-13-01767-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90ca/8473442/0da36ba26b97/viruses-13-01767-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90ca/8473442/0da36ba26b97/viruses-13-01767-g001.jpg

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New Approaches to the Treatment of Chronic Hepatitis B.慢性乙型肝炎治疗的新方法
J Clin Med. 2020 Oct 1;9(10):3187. doi: 10.3390/jcm9103187.
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Hepatitis B virus biology and life cycle.乙型肝炎病毒的生物学和生命周期。
Patient Prefer Adherence. 2023 Nov 30;17:3119-3124. doi: 10.2147/PPA.S433283. eCollection 2023.
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Small interfering RNA (siRNA)-based therapeutic applications against viruses: principles, potential, and challenges.基于小干扰 RNA(siRNA)的抗病毒治疗应用:原理、潜力和挑战。
J Biomed Sci. 2023 Oct 16;30(1):88. doi: 10.1186/s12929-023-00981-9.
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Mesenchymal stem cells-based therapy in liver diseases.基于间充质干细胞的肝脏疾病治疗
Mol Biomed. 2022 Jul 27;3(1):23. doi: 10.1186/s43556-022-00088-x.
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Virological Treatment Monitoring for Chronic Hepatitis B.慢性乙型肝炎的病毒学治疗监测。
Viruses. 2022 Jun 24;14(7):1376. doi: 10.3390/v14071376.
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