Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410078, China.
Hunan Provincial Key Laboratory of Clinical Epidemiology, Changsha 410078, China.
Nutrients. 2021 Aug 28;13(9):3012. doi: 10.3390/nu13093012.
There is a lack of evidence to show prevalence of laryngopharyngeal reflux (LPR) and the association between LPR and dietary factors. Adolescents consume the most amount of free sugars among the Chinese population. We conducted this study to investigate the prevalence of LPR in Chinese adolescents and explore the association between free sugars consumption and LPR. A cross-sectional study was conducted on 1517 middle school students in Hunan, China. An online questionnaire was applied to collect data on the condition of LPR, consumption of free sugars and other self-reported covariates. Height, weight and waist circumference were collected by anthropometric measurements. Logistic regression was applied to assess the association between LPR and free sugars consumption. The mean and standard deviation of free sugars consumption was 53.14 ± 44.75 (g/d). The prevalence of LPR was 8.11%. A positive association was observed between LPR and higher free sugars consumption after adjusted multiple covariates, with adjusted odds ratio (95% confident interval) of 1.656 (1.125-2.438). The prevalence of LPR among Chinese adolescents was high. Further analytic studies with strict design are required to test the association between LPR and free sugar consumption. Systematic strategies and policies should to be developed to reduce the intake of free sugars in order to prevent LPR.
目前尚无充分证据表明咽-喉反流(LPR)的流行情况以及 LPR 与饮食因素之间的关系。青少年是中国人中消耗游离糖最多的群体。本研究旨在调查中国青少年 LPR 的流行情况,并探讨游离糖摄入与 LPR 之间的关系。我们在中国湖南开展了一项横断面研究,纳入了 1517 名中学生。采用在线问卷调查收集 LPR 状况、游离糖摄入以及其他自报协变量等数据。通过人体测量法收集身高、体重和腰围。采用 logistic 回归分析评估 LPR 与游离糖摄入之间的关系。游离糖摄入量的平均值和标准差为 53.14 ± 44.75(g/d)。LPR 的患病率为 8.11%。经多变量调整后,LPR 与游离糖摄入呈正相关,调整后的比值比(95%置信区间)为 1.656(1.125-2.438)。中国青少年的 LPR 患病率较高。需要进一步进行严格设计的分析性研究来验证 LPR 与游离糖摄入之间的关系。应制定系统的策略和政策来减少游离糖的摄入,以预防 LPR。