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作为抗菌剂的亮氨酸衍生物席夫碱配合物的螯合与研究。

Amalgamation and Scrutinizing of Leucine Derivatives Schiff Bases Complexes as Antimicrobial Agent.

机构信息

Department of Chemistry, Government College University, Lahore 54000, Pakistan.

Department of Chemistry, University of Sahiwal, Sahiwal, Pakistan.

出版信息

Comb Chem High Throughput Screen. 2022;25(7):1167-1180. doi: 10.2174/1386207325666210927092623.

Abstract

The enhanced applications of Schiff bases metal complexes of amino acid derivatives have captured the attention of researchers for the synthesis of leucine derivatives of Schiff bases metal complexes. Amino acids are considered to be essential part of food supplements as well as derivatives of Schiff bases in coordination chemistry due to their donor ability. The leucine derivatives Schiff bases ligand have been synthesized by condensation reaction between amine of leucine with aldehyde or ketone bearing molecules attached with them. These complexes were characterized by different spectroscopic tools in order to confirm their structural geometries. The structural geometries are considered to be very important in order to improve the antimicrobial potential of leucine derivative metal complexes. By taking into account the antimicrobial potential of titled compounds, a comprehensive review of leucine derivatives of Schiff bases metal complexes has been compiled.

摘要

席夫碱金属配合物的应用得到了深入研究,其中氨基酸衍生物的席夫碱金属配合物的合成备受关注。由于氨基酸具有供电子能力,它们被认为是食品补充剂以及配位化学中席夫碱衍生物的重要组成部分。通过氨基酸的氨基与带有醛基或酮基的分子缩合反应,可以合成亮氨酸衍生物的席夫碱配体。这些配合物通过不同的光谱技术进行了表征,以确认它们的结构几何形状。结构几何形状对于提高亮氨酸衍生物金属配合物的抗菌潜力非常重要。考虑到标题化合物的抗菌潜力,我们对亮氨酸衍生物的席夫碱金属配合物进行了全面综述。

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