London M T, Chapman B A, Faoagali J L, Cook H B
N Z Med J. 1986 Apr 23;99(800):269-71.
There is little consensus concerning the incidence of bacteraemia during colonoscopy and the need for antibiotic prophylaxis in susceptible patients. Hepatic abscesses in one patient which may have been related to prior colonoscopic examinations led the authors to carry out a prospective study of 50 patients undergoing colonoscopy. Multiple blood cultures were carried out to maximise the positive yield of transient bacteraemia and to attempt to determine the time when bacteraemia is most likely to occur. Five patients had positive blood cultures. In two patients S epidermidis was isolated, but only from the precolonoscopic blood sample. In three subjects enteric organisms were cultured from blood samples obtained during the procedure. In one of these three the same organism was cultured from the preendoscopic blood sample so that in only two patients (4%) could the bacteraemia be attributed to the colonoscopy. These results would suggest that the risk of bacteraemia during colonoscopy is low.
关于结肠镜检查期间菌血症的发生率以及易感患者是否需要预防性使用抗生素，目前几乎没有共识。一名患者发生的肝脓肿可能与之前的结肠镜检查有关，这促使作者对50例接受结肠镜检查的患者进行了一项前瞻性研究。进行了多次血培养，以最大限度地提高短暂菌血症的阳性检出率，并试图确定菌血症最可能发生的时间。5例患者血培养呈阳性。2例患者分离出表皮葡萄球菌，但仅从结肠镜检查前的血样中分离出。在3名受试者中，从检查过程中采集的血样中培养出肠道细菌。在这3名患者中的1例中，结肠镜检查前的血样中也培养出了相同的细菌，因此只有2例患者（4%）的菌血症可归因于结肠镜检查。这些结果表明，结肠镜检查期间发生菌血症的风险较低。
