Low D E, Shoenut J P, Kennedy J K, Sharma G P, Harding G K, Den Boer B, Micflikier A B
Department of Medicine, St. Boniface General Hospital, Winnipeg, Manitoba, Canada.
Dig Dis Sci. 1987 Nov;32(11):1239-43. doi: 10.1007/BF01296372.
A prospective assessment was made of the frequency of positive blood cultures in patients undergoing colonoscopy with or without polypectomy. A total of 270 patients underwent 280 colonoscopies, of these, there were 105 patients that had 111 polypectomies. Blood cultures were taken prior to and within 15 min following each procedure. Six of 280 (2.1%) preprocedural blood cultures were positive. Seven of 169 (4%) blood cultures were positive within 15 min of insertion of the colonoscope in the colonoscopy only group. Eight of 223 (3.6%) blood cultures were positive within 10 min of the polypectomy. There was no clinical evidence of sepsis during the 24 hr following these procedures. In order to determine appropriate postprocedural sampling intervals, we induced a Staphylococcus epidermidis bacteremia with a mean of 1.16 X 10(6) colony forming units/ml on 10 occasions in seven dogs. Within 30 min of inoculation, we were able to detect only one colony forming unit/ml. The rate of positive blood cultures during colonoscopy alone and following polypectomy during colonoscopy is comparable to other gastrointestinal endoscopy procedures. The most optimal time to collect blood cultures in order to detect transient bacteremia is as soon after the procedure as is feasibly possible.
对接受或未接受息肉切除术的结肠镜检查患者血培养阳性的频率进行了前瞻性评估。共有270例患者接受了280次结肠镜检查，其中105例患者进行了111次息肉切除术。在每次操作前及操作后15分钟内采集血培养样本。280份术前血培养中有6份（2.1%）呈阳性。在仅进行结肠镜检查的组中，169份血培养中有7份（4%）在结肠镜插入结肠后15分钟内呈阳性。在息肉切除术后10分钟内，223份血培养中有8份（3.6%）呈阳性。在这些操作后的24小时内没有败血症的临床证据。为了确定合适的术后采样间隔，我们在7只犬身上进行了10次表皮葡萄球菌菌血症诱导，平均菌量为1.16×10(6)菌落形成单位/毫升。接种后30分钟内，我们仅能检测到1菌落形成单位/毫升。单纯结肠镜检查期间及结肠镜检查后息肉切除术后血培养阳性率与其他胃肠道内镜检查程序相当。为了检测短暂菌血症，采集血培养的最佳时间是在操作后尽可能早的时间。
