Crown Princess Victoria Children's Hospital, Linköping, Sweden.
Division of Community Medicine, Department of Medical and Health Sciences, Linköping University, SE-581 83, Linköping, Sweden.
J Clin Psychol Med Settings. 2022 Sep;29(3):489-497. doi: 10.1007/s10880-021-09822-z. Epub 2021 Sep 28.
Depressive symptoms after coronary events are associated with a worse prognosis. When changing the focus from psychopathology towards a resilience framework, treatments such as mindfulness meditation could offer novel ways to address psychological distress among coronary artery disease (CAD) patients. We studied the feasibility of mindfulness-based stress reduction (MBSR) for CAD patients with depressive symptoms. Seventy-nine CAD patients with elevated depressive symptoms were invited to an 8-week MBSR course. Twenty-four patients (30%) accepted and 16 (20%) completed MBSR. Depressive symptoms decreased immediately after the course (p = .006). After 12 months, this improvement remained, and Mastery scores increased (p = .005). A reference group of 108 CAD patients did not show any significant changes in depressive symptoms or Mastery between 1 and 12 months after a coronary event. MBSR thus appears to be a feasible alternative for CAD patients with elevated depressive symptoms. Future studies are warranted to study if MBSR can improve psychological functioning in CAD patients.Clinicaltrials.gov (Registration Number: NCT03340948).
冠心病患者发生抑郁症状与预后不良有关。当将研究重点从精神病理学转向韧性框架时，正念冥想等治疗方法可能为冠心病患者的心理困扰提供新的解决途径。我们研究了正念减压（MBSR）对冠心病伴抑郁症状患者的可行性。79 名有抑郁症状的冠心病患者被邀请参加为期 8 周的 MBSR 课程。24 名患者（30%）接受了课程，16 名（20%）完成了课程。课程结束后抑郁症状立即减轻（p = .006）。12 个月后，这种改善仍然存在，掌控感评分增加（p = .005）。在冠心病发作后 1 至 12 个月，对照组 108 名冠心病患者的抑郁症状或掌控感均无明显变化。因此，MBSR 似乎是冠心病伴抑郁症状患者的可行替代方法。未来的研究需要研究 MBSR 是否可以改善冠心病患者的心理功能。Clinicaltrials.gov（注册号：NCT03340948）。
