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2
Inhaled budesonide for COVID-19 in people at high risk of complications in the community in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial.在英国社区中有并发症高风险的人群中使用布地奈德吸入剂治疗 COVID-19(PRINCIPLE):一项随机、对照、开放标签、适应性平台试验。
Lancet. 2021 Sep 4;398(10303):843-855. doi: 10.1016/S0140-6736(21)01744-X. Epub 2021 Aug 10.
3
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5
Inhaled corticosteroid is not associated with a poor prognosis in COVID-19.吸入性皮质类固醇与 COVID-19 的不良预后无关。
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Inhaled corticosteroids do not adversely impact outcomes in COVID-19 positive patients with COPD: An analysis of Cleveland Clinic's COVID-19 registry.吸入性皮质类固醇不会对 COVID-19 合并 COPD 患者的结局产生不利影响:克利夫兰诊所 COVID-19 注册中心的分析。
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新冠病毒肺炎与慢性阻塞性肺疾病:疫情之外的教训

COVID-19 and COPD: lessons beyond the pandemic.

作者信息

Halpin David M G, Vogelmeier Claus F, Agusti Alvar

机构信息

University of Exeter Medical School, College of Medicine and Health, University of Exeter, Exeter, United Kingdom.

Department of Medicine, Pulmonary and Critical Care Medicine, University Medical Center Giessen and Marburg, Member of the German Center for Lung Research (DZL), Philipps-University Marburg, Marburg, Germany.

出版信息

Am J Physiol Lung Cell Mol Physiol. 2021 Nov 1;321(5):L978-L982. doi: 10.1152/ajplung.00386.2021. Epub 2021 Sep 29.

DOI:10.1152/ajplung.00386.2021
PMID:34585618
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8598249/
Abstract

Early in the COVID pandemic there were concerns about the outcomes for patients with COPD who developed COVID-19. Although the pandemic has made the diagnosis and routine management of COPD more difficult, the risk of patients developing COVID or of having poor outcomes is less than anticipated and there have been some unexpected findings that may lead to significant improvements in the management of COPD in future.

摘要

在新冠疫情初期,人们对慢性阻塞性肺疾病(COPD)患者感染新冠病毒后的预后情况表示担忧。尽管疫情使慢性阻塞性肺疾病的诊断和常规管理变得更加困难,但患者感染新冠病毒或预后不良的风险低于预期,并且出现了一些意外发现,这些发现可能会在未来显著改善慢性阻塞性肺疾病的管理。