新冠病毒肺炎与慢性阻塞性肺疾病：疫情之外的教训
COVID-19 and COPD: lessons beyond the pandemic.
作者信息
Halpin David M G, Vogelmeier Claus F, Agusti Alvar
机构信息
University of Exeter Medical School, College of Medicine and Health, University of Exeter, Exeter, United Kingdom.
Department of Medicine, Pulmonary and Critical Care Medicine, University Medical Center Giessen and Marburg, Member of the German Center for Lung Research (DZL), Philipps-University Marburg, Marburg, Germany.
出版信息
Am J Physiol Lung Cell Mol Physiol. 2021 Nov 1;321(5):L978-L982. doi: 10.1152/ajplung.00386.2021. Epub 2021 Sep 29.
Abstract
Early in the COVID pandemic there were concerns about the outcomes for patients with COPD who developed COVID-19. Although the pandemic has made the diagnosis and routine management of COPD more difficult, the risk of patients developing COVID or of having poor outcomes is less than anticipated and there have been some unexpected findings that may lead to significant improvements in the management of COPD in future.
摘要
在新冠疫情初期，人们对慢性阻塞性肺疾病（COPD）患者感染新冠病毒后的预后情况表示担忧。尽管疫情使慢性阻塞性肺疾病的诊断和常规管理变得更加困难，但患者感染新冠病毒或预后不良的风险低于预期，并且出现了一些意外发现，这些发现可能会在未来显著改善慢性阻塞性肺疾病的管理。
相似文献
1
COVID-19 and COPD: lessons beyond the pandemic.新冠病毒肺炎与慢性阻塞性肺疾病：疫情之外的教训
Am J Physiol Lung Cell Mol Physiol. 2021 Nov 1;321(5):L978-L982. doi: 10.1152/ajplung.00386.2021. Epub 2021 Sep 29.
2
[Asthma and COPD management during the COVID-19 pandemic].[COVID-19大流行期间的哮喘与慢性阻塞性肺疾病管理]
Rev Med Suisse. 2020 May 6;16(692):933-938.
3
Clinical Characteristics and Outcomes of Patients with Severe COVID-19 and Chronic Obstructive Pulmonary Disease (COPD).严重 COVID-19 和慢性阻塞性肺疾病（COPD）患者的临床特征和结局。
Med Sci Monit. 2020 Sep 4;26:e927212. doi: 10.12659/MSM.927212.
4
Social Distancing among COPD Patients during the COVID-19 Pandemic - A Qualitative Study.COVID-19 大流行期间 COPD 患者的社交隔离 - 一项定性研究。
COPD. 2021 Oct;18(5):549-556. doi: 10.1080/15412555.2021.1973981. Epub 2021 Sep 5.
5
Clinical Courses and Outcomes of Patients with Chronic Obstructive Pulmonary Disease During the COVID-19 Epidemic in Hubei, China.中国湖北省 COVID-19 流行期间慢性阻塞性肺疾病患者的临床病程和结局。
Int J Chron Obstruct Pulmon Dis. 2020 Sep 23;15:2237-2248. doi: 10.2147/COPD.S265004. eCollection 2020.
6
Synergistic effects of COVID-19 and Pseudomonas aeruginosa in chronic obstructive pulmonary disease: a polymicrobial perspective.COVID-19 与铜绿假单胞菌在慢性阻塞性肺疾病中的协同作用：一种多微生物角度。
Mol Cell Biochem. 2024 Mar;479(3):591-601. doi: 10.1007/s11010-023-04744-w. Epub 2023 May 2.
7
Impact of coronavirus disease-2019 on chronic respiratory disease in South Korea: an NHIS COVID-19 database cohort study.新型冠状病毒病 2019 对韩国慢性呼吸道疾病的影响：NHIS COVID-19 数据库队列研究。
BMC Pulm Med. 2021 Jan 6;21(1):12. doi: 10.1186/s12890-020-01387-1.
8
Focusing on Asthma and Chronic Obstructive Pulmonary Disease with COVID-19.聚焦 COVID-19 下的哮喘和慢性阻塞性肺疾病。
J Infect Dev Ctries. 2021 Oct 31;15(10):1415-1425. doi: 10.3855/jidc.14611.
9
Impact of the COVID-19 pandemic on the management of chronic noninfectious respiratory diseases.COVID-19 大流行对慢性非传染性呼吸系统疾病管理的影响。
Expert Rev Respir Med. 2021 Aug;15(8):1035-1048. doi: 10.1080/17476348.2021.1951707. Epub 2021 Jul 21.
10
Obstructive lung diseases burden and COVID-19 in developing countries: a perspective.发展中国家的阻塞性肺疾病负担和 COVID-19：一个视角。
Curr Opin Pulm Med. 2022 Mar 1;28(2):84-92. doi: 10.1097/MCP.0000000000000836.
引用本文的文献
1
Prevalence of Respiratory Syncytial Virus Infection in Hospitalized COPD Patients in Spain Between 2018-2022.2018年至2022年西班牙住院慢性阻塞性肺疾病患者呼吸道合胞病毒感染的患病率
Diseases. 2025 Jan 20;13(1):23. doi: 10.3390/diseases13010023.
2
Impact of the coronavirus disease 2019 pandemic on hospital admissions for idiopathic pulmonary fibrosis: a nationwide population-based study.2019 冠状病毒病大流行对特发性肺纤维化住院的影响：一项全国性基于人群的研究。
BMC Pulm Med. 2024 Aug 31;24(1):430. doi: 10.1186/s12890-024-03230-3.
3
COPD patients with high blood eosinophil counts exhibit a lower rate of omicron infection and milder post-infection symptoms.高血嗜酸性粒细胞计数的 COPD 患者感染奥密克戎的比例较低，感染后的症状也较轻。
Clin Respir J. 2024 Jun;18(6):e13790. doi: 10.1111/crj.13790.
4
Chronic Obstructive Pulmonary Disease Mortality and Hospitalization during the COVID-19 Pandemic Compared with before the Pandemic: A Systematic Review and Meta-Analysis.与大流行前相比，COVID-19大流行期间慢性阻塞性肺疾病的死亡率和住院率：一项系统评价和荟萃分析。
J Pers Med. 2024 Mar 10;14(3):296. doi: 10.3390/jpm14030296.
5
Physical Activity, Depression and Quality of Life in COPD - Results from the CLARA II Study.COPD 患者的体力活动、抑郁与生活质量 - CLARA II 研究结果。
Int J Chron Obstruct Pulmon Dis. 2023 Nov 29;18:2755-2767. doi: 10.2147/COPD.S435278. eCollection 2023.
6
Phytochemicals and Vitamin D for a Healthy Life and Prevention of Diseases.植物化学物质与维生素 D：健康生活与疾病预防
Int J Mol Sci. 2023 Jul 29;24(15):12167. doi: 10.3390/ijms241512167.
7
Organokines in COVID-19: A Systematic Review.COVID-19 中的器官激酶：系统评价。
Cells. 2023 May 9;12(10):1349. doi: 10.3390/cells12101349.
本文引用的文献
1
Ciclesonide Inhaler Treatment for Mild-to-Moderate COVID-19: A Randomized, Open-Label, Phase 2 Trial.环索奈德吸入器治疗轻至中度新冠肺炎：一项随机、开放标签的2期试验
J Clin Med. 2021 Aug 12;10(16):3545. doi: 10.3390/jcm10163545.
2
Inhaled budesonide for COVID-19 in people at high risk of complications in the community in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial.在英国社区中有并发症高风险的人群中使用布地奈德吸入剂治疗 COVID-19（PRINCIPLE）：一项随机、对照、开放标签、适应性平台试验。
Lancet. 2021 Sep 4;398(10303):843-855. doi: 10.1016/S0140-6736(21)01744-X. Epub 2021 Aug 10.
3
Antiviral Effect of Budesonide against SARS-CoV-2.布地奈德对 SARS-CoV-2 的抗病毒作用。
Viruses. 2021 Jul 20;13(7):1411. doi: 10.3390/v13071411.
4
Reduction in hospitalised COPD exacerbations during COVID-19: A systematic review and meta-analysis.在 COVID-19 期间减少住院 COPD 加重：系统评价和荟萃分析。
PLoS One. 2021 Aug 3;16(8):e0255659. doi: 10.1371/journal.pone.0255659. eCollection 2021.
5
Inhaled corticosteroid is not associated with a poor prognosis in COVID-19.吸入性皮质类固醇与 COVID-19 的不良预后无关。
Respirology. 2021 Aug;26(8):812-815. doi: 10.1111/resp.14108. Epub 2021 Jun 26.
6
Inhaled corticosteroids do not adversely impact outcomes in COVID-19 positive patients with COPD: An analysis of Cleveland Clinic's COVID-19 registry.吸入性皮质类固醇不会对 COVID-19 合并 COPD 患者的结局产生不利影响：克利夫兰诊所 COVID-19 注册中心的分析。
PLoS One. 2021 Jun 3;16(6):e0252576. doi: 10.1371/journal.pone.0252576. eCollection 2021.
7
Assessment of the Association of COPD and Asthma with In-Hospital Mortality in Patients with COVID-19. A Systematic Review, Meta-Analysis, and Meta-Regression Analysis.COPD和哮喘与COVID-19患者院内死亡率的关联评估。一项系统评价、荟萃分析和荟萃回归分析。
J Clin Med. 2021 May 13;10(10):2087. doi: 10.3390/jcm10102087.
8
Effect of COVID-19 pandemic on air quality: a study based on Air Quality Index.2019年冠状病毒病大流行对空气质量的影响：一项基于空气质量指数的研究
Environ Sci Pollut Res Int. 2021 Jul;28(27):35564-35583. doi: 10.1007/s11356-021-14462-9. Epub 2021 May 25.
9
Chronic respiratory diseases are predictors of severe outcome in COVID-19 hospitalised patients: a nationwide study.慢性呼吸系统疾病是 COVID-19 住院患者发生严重结局的预测因素：一项全国性研究。
Eur Respir J. 2021 Dec 9;58(6). doi: 10.1183/13993003.04474-2020. Print 2021 Dec.
10
Impact of COVID-19 lockdown on the incidence and mortality of acute exacerbations of chronic obstructive pulmonary disease: national interrupted time series analyses for Scotland and Wales.新冠疫情封锁对慢性阻塞性肺疾病急性加重发病率和死亡率的影响：苏格兰和威尔士的全国中断时间序列分析。
BMC Med. 2021 May 17;19(1):124. doi: 10.1186/s12916-021-02000-w.
Zotero 插件