Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Curr Opin Pulm Med. 2022 Mar 1;28(2):84-92. doi: 10.1097/MCP.0000000000000836.
Asthma and chronic obstructive pulmonary disease (COPD) are widely prevalent disorders, and important contributors to morbidity and mortality, in both developing and developed countries. It is conjectured that these obstructive lung diseases may have had more deleterious effects in developing nations during the 2019 coronavirus disease (COVID-19) pandemic. We provide an evidence-based perspective on the relationship between asthma/COPD prevalence and COVID-19 burden, and the impact of comorbid asthma/COPD on selected COVID-19 outcomes and healthcare utilization, with special reference to developing countries.
Developing countries with higher COPD (but not asthma) prevalence appear to have higher COVID-19 related mortality. Patients with asthma (but not COPD) in developing countries may be less likely to acquire COVID-19. Published literature suggests that the overall impact of comorbid asthma or COPD on adverse COVID-19 outcomes may be broadly similar between developed and developing nations.
There is paucity of information on interaction between asthma/COPD and COVID-19 in developing countries. Limited data suggest minor differences between developed and developing nations. In view of inadequacies in healthcare preparedness and delivery in several developing countries, there is a need to generate quality evidence to assess impact of obstructive lung diseases and COVID-19 on each other.
哮喘和慢性阻塞性肺疾病(COPD)在发展中国家和发达国家都是广泛存在的疾病,是发病率和死亡率的重要原因。据推测,在 2019 年冠状病毒病(COVID-19)大流行期间,这些阻塞性肺部疾病在发展中国家可能产生了更有害的影响。我们提供了一个基于证据的视角,探讨哮喘/COPD 患病率与 COVID-19 负担之间的关系,以及合并哮喘/COPD 对某些 COVID-19 结局和医疗保健利用的影响,特别提到了发展中国家。
COPD 患病率较高(但不是哮喘)的发展中国家似乎 COVID-19 相关死亡率更高。发展中国家的哮喘患者(但不是 COPD)不太可能感染 COVID-19。已发表的文献表明,合并哮喘或 COPD 对不良 COVID-19 结局的总体影响在发达国家和发展中国家之间可能大致相似。
关于哮喘/COPD 和 COVID-19 在发展中国家之间的相互作用,信息匮乏。有限的数据表明发达国家和发展中国家之间存在细微差异。鉴于一些发展中国家的医疗保健准备和提供存在不足,需要生成高质量的证据来评估阻塞性肺部疾病和 COVID-19 对彼此的影响。