• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

基于边界调优支持向量机(BT-SVM)的基因选择癌症预测分类器。

Boundaries tuned support vector machine (BT-SVM) classifier for cancer prediction from gene selection.

机构信息

Department of Computer Science, Sri Kaliswari College (Autonomous), Sivakasi, TamilNadu, India.

Department of Information Technology, Kalasalingam Academy of Research and Education, Krishnankoil, Tamil Nadu, India.

出版信息

Comput Methods Biomech Biomed Engin. 2022 May;25(7):794-807. doi: 10.1080/10255842.2021.1981300. Epub 2021 Sep 29.

DOI:10.1080/10255842.2021.1981300
PMID:34585639
Abstract

In recent days, the identified genes which are detecting cancer-causing diseases are plays a crucial part in the microarray data analysis. Huge volume of data required since the disease changed often. Conventional data mining techniques are lacking in space concern and time complexity. Based on big data the proposed work is executed. Using the ISPCA - Improved Supervised Principal Component Analysis, feature extraction is developed in this study. For gene expression, co-variance matrix is generated and through feature selection cancer classification is performed by IPSCA. Further feature selection process by boundaries tuned support vector machines (BT-SVM) classifier and modified particle swarm optimization with novel wrapper model algorithm are performed. The experimentation is carried out by utilizing different datasets like leukaemia, breast cancer dataset, brain cancer, colon, and lung carcinoma from the UCI repository. The proposed work is executed on six benchmark dataset for DNA microarray data in terms of accuracy, recall, and precision to evaluate the performance of the proposed work. For evaluating the proposed work effectiveness, it is compared with various traditional techniques and resulted in optimum accuracy, recall, precision and training time with and without feature selection effectively.

摘要

最近,在微阵列数据分析中,鉴定出的与癌症相关的基因在其中起着至关重要的作用。由于疾病经常发生变化,因此需要大量的数据。传统的数据挖掘技术在空间关注和时间复杂度方面存在不足。本研究基于大数据执行。使用改进的监督主成分分析(ISPCA)进行特征提取。对于基因表达,生成协方差矩阵,并通过 IPSCA 进行癌症分类。进一步通过边界调谐支持向量机(BT-SVM)分类器和带有新型包装模型算法的改进粒子群优化进行特征选择过程。实验利用来自 UCI 存储库的不同数据集(如白血病、乳腺癌数据集、脑癌、结肠和肺癌)进行。为了评估所提出的工作的性能,在六个基准 DNA 微阵列数据集上以准确性、召回率和精度为指标进行了评估。为了评估所提出的工作的有效性,将其与各种传统技术进行了比较,并在有和没有特征选择的情况下有效地获得了最佳的准确性、召回率、精度和训练时间。

相似文献

1
Boundaries tuned support vector machine (BT-SVM) classifier for cancer prediction from gene selection.基于边界调优支持向量机(BT-SVM)的基因选择癌症预测分类器。
Comput Methods Biomech Biomed Engin. 2022 May;25(7):794-807. doi: 10.1080/10255842.2021.1981300. Epub 2021 Sep 29.
2
Incorporating EBO-HSIC with SVM for Gene Selection Associated with Cervical Cancer Classification.将 EBO-HSIC 与 SVM 相结合,用于选择与宫颈癌分类相关的基因。
J Med Syst. 2018 Oct 6;42(11):225. doi: 10.1007/s10916-018-1092-5.
3
Top scoring pairs for feature selection in machine learning and applications to cancer outcome prediction.机器学习中特征选择的最佳评分对及其在癌症预后预测中的应用。
BMC Bioinformatics. 2011 Sep 23;12:375. doi: 10.1186/1471-2105-12-375.
4
Feature Selection and Classification of Clinical Datasets Using Bioinspired Algorithms and Super Learner.基于生物启发算法和超级学习者的临床数据集特征选择与分类。
Comput Math Methods Med. 2021 May 17;2021:6662420. doi: 10.1155/2021/6662420. eCollection 2021.
5
Diagnosis of Brain Metastases from Lung Cancer Using a Modified Electromagnetism like Mechanism Algorithm.基于改良电磁类机制算法诊断肺癌脑转移
J Med Syst. 2016 Jan;40(1):35. doi: 10.1007/s10916-015-0367-3. Epub 2015 Nov 14.
6
An Efficient Feature Selection Strategy Based on Multiple Support Vector Machine Technology with Gene Expression Data.基于基因表达数据的多支持向量机技术的高效特征选择策略。
Biomed Res Int. 2018 Aug 30;2018:7538204. doi: 10.1155/2018/7538204. eCollection 2018.
7
Cancer Feature Selection and Classification Using a Binary Quantum-Behaved Particle Swarm Optimization and Support Vector Machine.基于二进制量子行为粒子群优化算法和支持向量机的癌症特征选择与分类
Comput Math Methods Med. 2016;2016:3572705. doi: 10.1155/2016/3572705. Epub 2016 Aug 24.
8
The construction of support vector machine classifier using the firefly algorithm.基于萤火虫算法的支持向量机分类器构建。
Comput Intell Neurosci. 2015;2015:212719. doi: 10.1155/2015/212719. Epub 2015 Feb 23.
9
Improving Classification of Cancer and Mining Biomarkers from Gene Expression Profiles Using Hybrid Optimization Algorithms and Fuzzy Support Vector Machine.使用混合优化算法和模糊支持向量机改进癌症分类并从基因表达谱中挖掘生物标志物
J Med Signals Sens. 2018 Jan-Mar;8(1):1-11.
10
Two-stage feature selection for classification of gene expression data based on an improved Salp Swarm Algorithm.基于改进的鹽蝽群算法的基因表达数据分类的两阶段特征选择
Math Biosci Eng. 2022 Sep 19;19(12):13747-13781. doi: 10.3934/mbe.2022641.

引用本文的文献

1
Identification of diagnostic markers pyrodeath-related genes in non-alcoholic fatty liver disease based on machine learning and experiment validation.基于机器学习和实验验证的非酒精性脂肪性肝病 pyroptosis 相关基因诊断标志物的鉴定。
Sci Rep. 2024 Oct 26;14(1):25541. doi: 10.1038/s41598-024-77409-3.
2
Identification of diagnostic markers and molecular clusters of cuproptosis-related genes in alcohol-related liver disease based on machine learning and experimental validation.基于机器学习和实验验证的酒精性肝病中铜死亡相关基因的诊断标志物和分子簇的鉴定
Heliyon. 2024 Sep 12;10(18):e37612. doi: 10.1016/j.heliyon.2024.e37612. eCollection 2024 Sep 30.
3
Identification and validation of potential diagnostic signature and immune cell infiltration for NAFLD based on cuproptosis-related genes by bioinformatics analysis and machine learning.
基于铜死亡相关基因的生物信息学分析和机器学习鉴定和验证非酒精性脂肪性肝病的潜在诊断标志物和免疫细胞浸润。
Front Immunol. 2023 Sep 26;14:1251750. doi: 10.3389/fimmu.2023.1251750. eCollection 2023.
4
Diagnostic signature, subtype classification, and immune infiltration of key m6A regulators in osteomyelitis patients.骨髓炎患者关键m6A调节因子的诊断特征、亚型分类及免疫浸润
Front Genet. 2022 Dec 5;13:1044264. doi: 10.3389/fgene.2022.1044264. eCollection 2022.