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以急性出血性中风为表现的肺吸虫病。

Paragonimiasis presenting as an acute hemorrhagic stroke.

作者信息

Paranjape Neha, Nunez Victor, Dicks Demetrius

机构信息

Wellstar Infectious Disease, Marietta, GA, USA.

Quantum Radiology, Marietta, GA, USA.

出版信息

IDCases. 2021 Sep 15;26:e01287. doi: 10.1016/j.idcr.2021.e01287. eCollection 2021.

DOI:10.1016/j.idcr.2021.e01287
PMID:34589413
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8461369/
Abstract

Cerebral paragonimiasis is rare and is usually seen in younger patients. This is a case of a 19-year-old male presenting as a hemorrhagic stroke with headache and blurred vision. He was found to have cystic thick-walled spaces with focal linear tracking towards the pleural space on computed tomography of the chest. CSF analysis showed pleocytosis with 4% eosinophils. Serological testing confirmed the diagnosis of paragonimiasis. He was treated with praziquantel, corticosteroid taper and anti-epileptic medication and discharged home in stable condition. CNS paragonimiasis is treatable, has a fairly good prognosis but can often be missed. In a young person presenting with an acute hemorrhagic stroke, the possibility of paragonimiasis should be kept on the differential diagnosis.

摘要

脑肺吸虫病较为罕见,通常见于年轻患者。这是一例19岁男性患者,表现为出血性中风,伴有头痛和视力模糊。胸部计算机断层扫描显示其有囊性厚壁腔隙,并向胸膜腔有局灶性线性延伸。脑脊液分析显示细胞增多,嗜酸性粒细胞占4%。血清学检测确诊为肺吸虫病。他接受了吡喹酮、逐渐减量的皮质类固醇和抗癫痫药物治疗,出院时病情稳定。中枢神经系统肺吸虫病是可治疗的,预后相当良好,但常常容易被漏诊。对于出现急性出血性中风的年轻人,应将肺吸虫病列入鉴别诊断的考虑范围。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c77/8461369/5b0c5bbc79e2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c77/8461369/498952b85a78/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c77/8461369/5b0c5bbc79e2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c77/8461369/498952b85a78/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c77/8461369/5b0c5bbc79e2/gr2.jpg

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本文引用的文献

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Cerebral paragonimiasis: a retrospective analysis of 27 cases.脑型肺吸虫病:27例回顾性分析
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2
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Stroke. 2014 Nov;45(11):3420-2. doi: 10.1161/STROKEAHA.114.007267. Epub 2014 Sep 30.
3
Serological diagnosis of North American Paragonimiasis by Western blot using Paragonimus kellicotti adult worm antigen.应用 Paragonimus kellicotti 成虫抗原的 Western blot 对北美肺吸虫病进行血清学诊断。
Am J Trop Med Hyg. 2013 Jun;88(6):1035-40. doi: 10.4269/ajtmh.12-0720. Epub 2013 Apr 15.
4
Cerebral paragonimiasis: a retrospective analysis of 89 cases.脑型肺吸虫病:89例回顾性分析
Clin Neurol Neurosurg. 2013 May;115(5):546-51. doi: 10.1016/j.clineuro.2012.06.025. Epub 2012 Jul 13.
5
Persisting antibody reaction in paragonimiasis after praziquantel treatment is elicited mainly by egg antigens.吡喹酮治疗后肺吸虫病中持续存在的抗体反应主要由虫卵抗原引起。
Korean J Parasitol. 2000 Jun;38(2):75-84. doi: 10.3347/kjp.2000.38.2.75.
6
Pleuropulmonary paragonimiasis: radiologic findings in 71 patients.胸膜肺型并殖吸虫病:71例患者的影像学表现
AJR Am J Roentgenol. 1992 Jul;159(1):39-43. doi: 10.2214/ajr.159.1.1609718.