Social media use and systemic inflammation: The moderating role of self-esteem.

Social media use has become an important part of social life. However, little is known about its relation to physical health. Extending prior work on social media use and psychological well-being, the present research investigated how social media use is associated with a key indicator of health, systemic inflammation. Based on research on self-esteem and work on inflammation, the current study examined whether the link between social media use and inflammatory biomarkers would be moderated by self-esteem. A nationally probablistic sample of middle-aged adults ( ​= ​863) completed self-report questionnaires on social media use, self-esteem, socio-demographic information, and health related behaviors. Approximately two years later, they provided a blood sample that was analyzed for C-reactive protein (CRP) and interleukin-6 (IL-6), biomarkers of systemic inflammation. Consistent with our hypothesis, self-esteem moderated the association between social media use and these markers of inflammation. Specifically, as self-esteem decreased, the positive association of social media use with CRP and IL-6 became stronger. These results held after controlling for socio-demographic information, health status, depressive symptoms, and medication usage. Social media use was not significantly correlated with either CRP or IL-6. The present research demonstrates physical health correlates of social media use and suggests self-esteem as a key variable that can moderate the relation between social media use and health.