基于 ZnO@富勒醇的共价反应触发光电流极性转换的白细胞介素-6 的光电化学免疫分析。
Photoelectrochemical immunoassay of interleukin-6 based on covalent reaction-triggered photocurrent polarity switching of ZnO@fullerenol.
机构信息
Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education of China), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, China.
出版信息
Chem Commun (Camb). 2021 Oct 19;57(83):10903-10906. doi: 10.1039/d1cc04820a.
We report here a novel photocurrent polarity switching strategy for a photoelectrochemical immunoassay driven by the covalent reaction between fullerenol (COH) and chloranilic acid (CA). The sensitive detection of interleukin-6 is achieved by using CA-encapsulated liposome as the label and COH-coated ZnO as the photoactive material, with a detection limit of 1.0 fg mL.
我们在此报告了一种新型的光电流极性转换策略，用于基于富勒醇（COH）和氯代邻苯二甲酸（CA）之间的共价反应驱动的光电化学免疫分析。通过使用 CA 包封的脂质体作为标记物和 COH 涂覆的 ZnO 作为光活性材料，实现了对白细胞介素-6 的灵敏检测，检测限为 1.0 fg mL。
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