Poverty, Health, and Nutrition Division, International Food Policy Research Institute, Washington, DC, USA.
J Nutr. 2021 Dec 3;151(12):3841-3855. doi: 10.1093/jn/nxab292.
Poor birth outcomes are an important global public health problem. Social assistance programs that provide cash or in-kind transfers, such as food or vouchers, hold potential to improve birth outcomes but the evidence on their effectiveness has not been reviewed.
We systematically reviewed studies that used experimental or quasi-experimental methods to evaluate the impacts of social assistance programs on outcomes in low- and middle-income countries.
The Grading of Recommendations, Assessment, Development and Evaluations (GRADE) system was used to assess the certainty of the evidence for birth weight and neonatal mortality (most common outcomes reported). We summarized the evidence on hypothesized nutrition and health pathways of impact.
We included 6 evaluations of 4 different cash transfer programs and 1 evaluation of a community-based participatory learning and action program that provided food and cash transfers. The 4 studies that assessed birth weight impacts found significant (P < 0.05) effects ranging from 31 to 578 g. Out of 3 studies that assessed neonatal mortality impacts, 2 found significant effects ranging from 0.6 to 3.1 deaths/1000 live births. The certainty of the evidence for both outcomes was rated as very low due to several methodological limitations. In terms of potential pathways, some studies documented positive effects on maternal diet, antenatal care (ANC) utilization, and delivery in a health facility.
Better-designed evaluations are needed to strengthen the evidence base on these programs. Evaluation studies should elucidate underlying mechanisms of impact by including outcomes related to maternal diet, ANC seeking, use of skilled delivery, and women's empowerment in nutrition and health domains. Studies should also assess potential unintended negative consequences of social assistance, such as reduced birth spacing and excess pregnancy weight gain.
不良出生结局是一个重要的全球公共卫生问题。提供现金或实物转移(如食品或代金券)的社会援助计划有可能改善出生结局,但关于其有效性的证据尚未得到审查。
我们系统地审查了使用实验或准实验方法评估社会援助计划对中低收入国家结局影响的研究。
使用推荐评估、发展和评估分级(GRADE)系统评估出生体重和新生儿死亡率(最常报告的结局)的证据确定性。我们总结了假设的营养和健康影响途径的证据。
我们纳入了 4 项不同现金转移计划的 6 项评估和 1 项提供食品和现金转移的基于社区的参与式学习和行动计划的评估。4 项评估出生体重影响的研究发现,效果有显著差异(P<0.05),范围从 31 克到 578 克。在评估新生儿死亡率影响的 3 项研究中,有 2 项发现了显著效果,范围从每 1000 例活产 0.6 例到 3.1 例死亡。由于存在若干方法学局限性,这两个结局的证据确定性被评为极低。就潜在途径而言,一些研究记录了对产妇饮食、产前护理(ANC)利用以及在医疗机构分娩的积极影响。
需要更好设计的评估来加强这些计划的证据基础。评估研究应阐明影响的潜在机制,包括与产妇饮食、ANC 寻求、熟练分娩利用以及妇女在营养和健康领域的赋权相关的结局。研究还应评估社会援助的潜在意外负面后果,如生育间隔缩短和妊娠体重过度增加。