Chemistry Department, Faculty of Pharmacy, October 6 University, 6 October City, 12585, Giza, Egypt.
Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr-El Aini Street, 11562, Cairo, Egypt.
Anal Methods. 2021 Oct 28;13(41):4896-4903. doi: 10.1039/d1ay01212f.
Food additives are chemicals added to enhance the appearance, taste, or lifetime of food products. Authorities continuously update the lists of the allowed additives and their daily intake limits. Thus, authorities and food suppliers strictly monitor additives in food products to guarantee their safety and compliance with national laws and safety criteria. The daily intake of the food colorant sunset yellow is banned in some countries and strictly controlled in others. Herein, a chemically modified solid-state potentiometric sensor was fabricated and used for the direct, fast, sensitive and selective assay of sunset yellow in soft drink and pharmaceutical formulation samples. The study optimized the sensor composition and the optimized carbon paste included a novel polymeric ion-exchanger, dioctyl phthalate, chitosan, and calix-[8]-arene and produced a rapid and near-Nernstian response of -32.9 ± 0.821 mV per decade for sunset yellow in the concentration range 7.94 × 10 M to 1.0 × 10 M and in the pH range 5-10. The sensor revealed good selectivity toward sunset yellow in the presence of commonly encountered ionic species. The method was validated according to the International Council for Harmonization guidelines and the results were statistically comparable to those of a reported method. The solid-state sensor represents a tool for fast and direct assay of sunset yellow in food products without sample pretreatment.
食品添加剂是为了增强食品产品的外观、口感或保质期而添加的化学物质。有关部门不断更新允许使用的添加剂及其每日摄入量限制的清单。因此，有关部门和食品供应商严格监控食品产品中的添加剂，以保证其安全性，并符合国家法律和安全标准。一些国家禁止在某些食品中添加日落黄这种食品着色剂，而另一些国家则对其进行严格控制。在此，我们制备了一种化学修饰的固态电位传感器，并将其用于直接、快速、灵敏和选择性测定软饮料和药物制剂样品中的日落黄。该研究优化了传感器的组成，优化后的碳糊电极包含一种新型聚合物离子交换剂邻苯二甲酸二辛酯、壳聚糖和杯[8]芳烃，并在 7.94×10 M 至 1.0×10 M 的浓度范围内和 pH 值为 5-10 时，对日落黄产生了快速且接近 Nernst 的响应，为-32.9±0.821 mV/decade。该传感器在存在常见离子种类的情况下对日落黄具有良好的选择性。该方法根据国际协调委员会的指导方针进行了验证，结果在统计学上与已报道的方法可比。固态传感器代表了一种无需样品预处理即可快速直接测定食品中日落黄的工具。
