67Ga标记的N-羟基氨基酸衍生物在荷瘤大鼠体内的生物分布
The biodistribution of 67Ga-labelled N-hydroxyamino acid derivatives in tumour-bearing rats.
作者信息
Herscheid J D, Knops G H, Hoekstra M
出版信息
Nucl Med Commun. 1986 Jan;7(1):53-7. doi: 10.1097/00006231-198601000-00007.
Abstract
The biodistribution of 67Ga-labelled complexes of some mono- and di-N-hydroxyamino acid derivatives and of two siderophores (trihydroxamates) were evaluated in Rhabdomyosarcoma-bearing rats. It was found that the mono- and dihydroxamates could not enhance the tumour-localizing properties of 67Ga-citrate, while the 67Ga-labelled trihydroxamates showed very rapid urinary excretion.
摘要
在患有横纹肌肉瘤的大鼠中评估了一些单-N-羟基氨基酸衍生物和二-N-羟基氨基酸衍生物以及两种铁载体（三羟基肟酸）的67Ga标记配合物的生物分布。结果发现，单羟基肟酸和二羟基肟酸不能增强67Ga-柠檬酸盐的肿瘤定位特性，而67Ga标记的三羟基肟酸显示出非常快速的尿排泄。
Zotero 插件