“彩虹图案”：一种侵袭性黑色素瘤的皮肤镜征象。

'Rainbow pattern': a dermoscopic sign of invasive melanoma.

机构信息

Dermatology and Venereology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

Department of Dermatology and Venereology, Hospital Universitario de Móstoles, Madrid, Spain.

出版信息

Clin Exp Dermatol. 2022 Mar;47(3):529-533. doi: 10.1111/ced.14950. Epub 2021 Nov 10.

DOI:10.1111/ced.14950

PMID:34592008

Abstract

BACKGROUND

The 'rainbow pattern' was initially described as a highly specific dermoscopic feature of Kaposi sarcoma. Since then, it has been reported in many benign and malignant cutaneous tumours, including a few malignant melanomas (MMs).

AIM

To determine the frequency and presentation of this dermoscopic pattern in primary cutaneous MMs in comparison to other cutaneous tumours.

METHODS

The presence of a rainbow pattern was evaluated in a sample of 1100 dermoscopic images of different melanocytic and nonmelanocytic cutaneous neoplasms.

RESULTS

The rainbow pattern was observed in 23 of 245 (9.4%) MM and 44 of 855 (5.1%) non-MM neoplasms. MMs presenting this feature were generally thicker: 82.6% > 1 mm and 43.0% > 2 mm. Compared with non-MMs, rainbow pattern in MMs was more commonly focal (82.7% vs. 36.4% nonfocal, P = 0.001) and associated with > 2 dermoscopic structures associated with MM (100% vs. 9% with fewer, P = 0.001).

CONCLUSION

The rainbow pattern is a dermoscopic sign that can occasionally be observed in invasive MMs. In MMs, this feature is usually associated with other dermoscopic criteria of MM and located in a focal and eccentric area, as opposed to a diffuse and isolated presentation in non-MM neoplasms.

摘要

背景

“彩虹图案”最初被描述为卡波西肉瘤的一种高度特异性皮肤镜特征。此后，它已在许多良性和恶性皮肤肿瘤中被报道，包括少数恶性黑色素瘤（MM）。

目的

确定原发性皮肤 MM 中这种皮肤镜特征的频率和表现，并与其他皮肤肿瘤进行比较。

方法

评估了 1100 张不同黑素细胞和非黑素细胞皮肤肿瘤的皮肤镜图像样本中彩虹图案的存在。

结果

在 245 例 MM 中的 23 例（9.4%）和 855 例非-MM 肿瘤中的 44 例（5.1%）中观察到彩虹图案。呈现这种特征的 MM 通常较厚：82.6% > 1mm 和 43.0% > 2mm。与非-MM 肿瘤相比，MM 中的彩虹图案更常见为局灶性（82.7% vs. 36.4%非局灶性，P = 0.001），并与 > 2 个与 MM 相关的皮肤镜结构相关（100% vs. 9%具有较少的结构，P = 0.001）。