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皮肤镜在黑色素瘤检测中的多重作用。

The Many Roles of Dermoscopy in Melanoma Detection.

作者信息

Jitian Mihulecea Cristina-Raluca, Iancu Gabriela Mariana, Leventer Mihaela, Rotaru Maria

机构信息

Doctoral Studies, Victor Babeș University of Medicine and Pharmacy of Timișoara, 300041 Timișoara, Romania.

Dermatology Clinic, Emergency Clinical County Hospital of Sibiu, 550245 Sibiu, Romania.

出版信息

Life (Basel). 2023 Feb 9;13(2):477. doi: 10.3390/life13020477.

Abstract

Dermoscopy is a non-invasive method of examination that aids the clinician in many ways, especially in early skin cancer detection. Melanoma is one of the most aggressive forms of skin cancer that can affect individuals of any age, having an increasing incidence worldwide. The gold standard for melanoma diagnosis is histopathological examination, but dermoscopy is also very important for its detection. To highlight the many roles of dermoscopy, we analyzed 200 melanocytic lesions. The main objective of this study was to detect through dermoscopy hints of melanomagenesis in the studied lot. The most suspicious were 10 lesions which proved to be melanomas confirmed through histopathology. The second objective of this study was to establish if dermoscopy can aid in estimating the Breslow index (tumoral thickness) of the melanomas and to compare the results to the histopathological examination. We found that the tumoral thickness may be estimated through dermoscopy, but the histopathological examination is superior. To conclude, the aim of this study was to showcase the versatility and many roles of dermoscopy, besides being one of the most important tools for early melanoma diagnosis.

摘要

皮肤镜检查是一种非侵入性检查方法,在许多方面对临床医生有帮助,尤其是在早期皮肤癌检测方面。黑色素瘤是最具侵袭性的皮肤癌形式之一,可影响任何年龄段的个体,在全球范围内发病率不断上升。黑色素瘤诊断的金标准是组织病理学检查,但皮肤镜检查对其检测也非常重要。为了突出皮肤镜检查的诸多作用,我们分析了200个黑素细胞性病变。本研究的主要目的是通过皮肤镜检查在所研究的病例组中发现黑色素瘤发生的线索。最可疑的是10个病变,经组织病理学证实为黑色素瘤。本研究的第二个目的是确定皮肤镜检查是否有助于估计黑色素瘤的 Breslow 指数(肿瘤厚度),并将结果与组织病理学检查进行比较。我们发现肿瘤厚度可以通过皮肤镜检查估计,但组织病理学检查更具优势。总之,本研究的目的是展示皮肤镜检查的多功能性和诸多作用,它是早期黑色素瘤诊断的最重要工具之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aed5/9964307/97baf0ffa853/life-13-00477-g001.jpg

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