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评估印度浦那地区医院 6 周随访时剖宫产和阴道分娩产妇产后抑郁的差异:一项观察性队列研究。

Assessment of difference in postpartum depression among caesarean and vaginally delivered women at 6-week follow-up in hospitals in Pune District, India: an observational cohort study.

机构信息

Community Medicine, Bharati Vidyapeeth Deemed University Medical College, Pune, India.

Community Medicine, Bharati Vidyapeeth Deemed University Medical College, Pune, India

出版信息

BMJ Open. 2021 Sep 30;11(9):e052008. doi: 10.1136/bmjopen-2021-052008.

DOI:10.1136/bmjopen-2021-052008
PMID:34593503
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8487184/
Abstract

OBJECTIVES

To compare the proportion of postpartum depression at 6 weeks among women who had caesarean delivery and women who had vaginal delivery and to assess its association with some sociodemographic factors.

DESIGN

This is a descriptive comparative study with prospective enrolment. We followed the enrolled women and assessed them for postpartum depression 6 weeks after delivery.

SETTING

We conducted the study in Pune District, India from July 2017 to December 2018. The study sites were all non-teaching government hospitals performing five or more caesarean sections per month and two teaching hospitals: one government and one private.

PARTICIPANTS

We included in the study group women who have undergone caesarean section in the participating hospitals and were residents of Pune District. Women who delivered vaginally and matched in age and parity were included in the comparison group. We followed 1556 women in each group.

MAIN OUTCOME MEASURES

An Edinburgh Postnatal Depression Scale score of 10 or more for each woman was the primary outcome. χ test and multivariable binary logistic regression were performed to assess the effect of mode of delivery on postpartum depression.

RESULTS

The proportion of postpartum depression at 6 weeks was 3.79% among women who had caesarean delivery and 2.35% among those who had vaginal delivery (χ=4.50, p=0.03). The adjusted OR was 1.86 (95% CI 1.14 to 3.03). Women of age less than 25 years had higher risk of postpartum depression. The adjusted OR was 2.10 (95% CI 1.21 to 3.65). The study did not observe any association between postpartum depression and income, education, occupation or sex of the newborn child.

CONCLUSIONS

We conclude that young women particularly those who had caesarean delivery should be screened 6 weeks after delivery.

摘要

目的

比较剖宫产与阴道分娩产妇产后 6 周抑郁的比例,并评估其与一些社会人口因素的关系。

设计

这是一项具有前瞻性纳入的描述性比较研究。我们随访了入组的女性,并在产后 6 周时评估了她们的产后抑郁情况。

地点

我们于 2017 年 7 月至 2018 年 12 月在印度浦那地区开展了这项研究。研究地点均为每月行 5 例或以上剖宫产术的非教学性政府医院,以及两家教学医院:一家公立医院和一家私立医院。

参与者

我们将在参与医院行剖宫产术且为浦那地区居民的女性纳入研究组,将年龄和产次匹配的阴道分娩女性纳入对照组。每组我们都随访了 1556 名女性。

主要结局测量

每位女性的爱丁堡产后抑郁量表评分达到 10 分或以上为主要结局。采用 χ²检验和多变量二项逻辑回归分析评估分娩方式对产后抑郁的影响。

结果

剖宫产组产后 6 周抑郁的比例为 3.79%,阴道分娩组为 2.35%(χ²=4.50,p=0.03)。调整后的 OR 为 1.86(95%CI 1.143.03)。年龄小于 25 岁的女性产后抑郁风险较高,调整后的 OR 为 2.10(95%CI 1.213.65)。本研究未观察到产后抑郁与收入、教育、职业或新生儿性别之间存在任何关联。

结论

我们的结论是,年轻女性,尤其是行剖宫产术的女性,应在产后 6 周时进行筛查。

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