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预制尿道与预植入尿道板治疗重度尿道下裂患儿阴茎外观及结局的比较:一项回顾性研究

Comparison of Penile Appearance and Outcomes Between Prefabricated Urethra and Pre-implanted Urethral Plate for Treatment of Children With Severe Hypospadias: A Retrospective Study.

作者信息

Ding Yuan, Gu Shengli, Xia Xingrong, Yu Zhengbo

机构信息

Pediatric Surgery, The First People's Hospital of Zunyi (The Third Affiliated Hospital of Zunyi Medical University), Zunyi, China.

出版信息

Front Pediatr. 2021 Sep 14;9:719551. doi: 10.3389/fped.2021.719551. eCollection 2021.

Abstract

To compare the effect of prefabricated urethra and pre-implanted urethral plate in the treatment of severe hypospadias in children. We retrospectively analyzed the clinical data of 53 patients who diagnosed as severe hypospadias underwent staging urethroplasty from January 2015 to January 2018 in the Department of Pediatric Surgery, First People's Hospital, Zunyi City. The patients were divided into two groups: group A ( = 25) were treated with prefabricated urethra and group B ( = 28) were treated with pre-implanted urethral plate. After the second stage surgery, the ratios of complications such as urethral fistula, urethral stenosis, urethrocele, and recurrence chordee were compared. The penis was scored from meatus, glans, shaft skin, general appearance by the parents, blinded urologists according to The Pediatric Penile Perception Score, and the scores were compared too. All patients were followed up after two stage operations for an average of 28 months. Glans dehiscence occurred in two patients (8%), urethral orifice stenosis occurred in one (4%) and urethral fistula occurred in three (12%) in group A. No urethral stenosis, urethrocele and recurrence chordee was observed. One patient presented urethral plate inactivation (3.6%), two patients presented urethral fistula (7.1%) and one patient presented urethral stenosis (3.6%) in group B. No urethrocele, glans dehiscence and recurrence chordee was observed. The total complication rate in group A was 24 and 14.3% in group B, respectively, and the difference was not statistically significant ( = 0.582). The differences between two groups scored by parents in glans ( = 0.030) was statistically significant. The differences between two groups scored by operators in meatus ( = 0.041), shaft skin ( = 0.000), glans ( = 0.001), and general appearance ( = 0.007) were statistically significant. The differences between two groups scored by counterparts in meatus ( = 0.006), shaft skin ( = 0.003), glans ( = 0.010), and general appearance ( = 0.014) were statistically significant. Both prefabricated urethra and pre-implanted urethral plate methods are suitable for correction of severe hypospadias as staging surgery in children. In general, pre-implanted urethral plate is more worthy of spread because it is much more applied in patients with small glans and achieve good appearance of penis.

摘要

比较预制尿道和预植入尿道板治疗小儿重度尿道下裂的效果。回顾性分析2015年1月至2018年1月遵义市第一人民医院小儿外科收治的53例诊断为重度尿道下裂并接受分期尿道成形术患者的临床资料。将患者分为两组:A组(n = 25)采用预制尿道治疗,B组(n = 28)采用预植入尿道板治疗。二期手术后,比较两组尿道瘘、尿道狭窄、尿道膨出和阴茎下弯复发等并发症的发生率。按照小儿阴茎感知评分法,由家长、不知情的泌尿外科医生分别从尿道口、龟头、阴茎体皮肤、整体外观对阴茎进行评分,并比较两组评分。所有患者二期手术后平均随访28个月。A组有2例(8%)发生龟头裂开,1例(4%)发生尿道口狭窄,3例(12%)发生尿道瘘。未观察到尿道狭窄、尿道膨出和阴茎下弯复发。B组有1例(3.6%)发生尿道板失活,2例(7.1%)发生尿道瘘,1例(3.6%)发生尿道狭窄。未观察到尿道膨出、龟头裂开和阴茎下弯复发。A组总并发症发生率为24%,B组为14.3%,差异无统计学意义(P = 0.582)。家长对两组龟头评分的差异有统计学意义(P = 0.030)。术者对两组尿道口(P = 0.041)、阴茎体皮肤(P = 0.000)、龟头(P = 0.001)及整体外观(P = 0.007)评分的差异有统计学意义。同行对两组尿道口(P = 0.006)、阴茎体皮肤(P = 0.003)、龟头(P = 0.010)及整体外观(P = 0.014)评分的差异有统计学意义。预制尿道和预植入尿道板两种方法均适用于小儿重度尿道下裂分期手术矫正。总体而言,预植入尿道板更值得推广,因为其在小龟头患者中应用更多,且阴茎外观良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4f5/8476890/097186143705/fped-09-719551-g0001.jpg

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