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采用横断尿道板和横行包皮岛状皮瓣(TPIF)对重度尿道下裂进行一期与新型二期尿道成形术的比较研究:单中心经验

Comparative study of one-stage and the novel two-stage urethroplasty using the transected urethral plate and transverse preputial island flap (TPIF) for severe hypospadias: a single-center experience.

作者信息

Zhu Xiaojiang, Huang Liqu, Wang Jun, Zhu Haobo, Chen Chenjun, Wang Lixia, Deng Yongji, Ma Geng, Guo Yunfei, Ge Zheng

机构信息

Department of Urology, Children's Hospital of Nanjing Medical University, Nanjing, China.

出版信息

Transl Pediatr. 2021 Apr;10(4):843-850. doi: 10.21037/tp-20-392.

Abstract

BACKGROUND

To evaluate a novel two-stage method of urethroplasty using a transected urethral plate and transverse preputial island flap (TPIF) for proximal hypospadias with severe chordee.

METHODS

We retrospectively analyzed 91 cases of proximal hypospadias, who had undergone either one-stage or two-stage urethroplasty. Comparisons between the two groups were made based on age, glans diameter, the length of the urethral defect, and the rate of complications.

RESULTS

There was no significant difference in age at surgery, glans diameter, and the length of urethral defect between the two groups. In the one-stage group, 18 cases of urinary fistula and one case each of glans dehiscence, urethral diverticulum, and urethral diverticulum with concurrent glans dehiscence, were reported. All patients were treated using urinary fistula repair or urethroplasty. In the novel two-stage group, no cases of urinary fistula were reported after the secondary urethroplasty. However, 4 cases showed dehiscence at the glans, 2 were treated through reoperation but the 2 other 2 patients reoperation. The success rate was 62.50% and 88.57% in the one-stage and two-stage groups, respectively (P<0.05).

CONCLUSIONS

Two-stage urethroplasty using a tubularized urethral plate and TPIF can significantly reduce the incidence of urethral fistula of the proximal hypospadias with severe chordee. However, it may increase the number of operations that need to be performed on children who do not need staged surgery. Although we could not prove it through this study, we believe that the necessity of two-stage urethroplasty should be determined based on the development of the glans, the severity of penile curvature, and the length of the urethra defect.

摘要

背景

评估一种新型两阶段尿道成形术的方法,该方法使用横断尿道板和横向包皮岛状皮瓣(TPIF)治疗伴有严重阴茎下弯的近端尿道下裂。

方法

我们回顾性分析了91例接受一期或两阶段尿道成形术的近端尿道下裂患者。基于年龄、龟头直径、尿道缺损长度和并发症发生率对两组进行比较。

结果

两组患者的手术年龄、龟头直径和尿道缺损长度无显著差异。在一期手术组中,报告了18例尿瘘,以及各1例龟头裂开、尿道憩室和并发龟头裂开的尿道憩室。所有患者均接受尿瘘修复或尿道成形术治疗。在新型两阶段手术组中,二期尿道成形术后未报告尿瘘病例。然而,有4例出现龟头裂开,2例通过再次手术治疗,但另外2例未进行再次手术。一期和两阶段手术组的成功率分别为62.50%和88.57%(P<0.05)。

结论

使用管状尿道板和TPIF的两阶段尿道成形术可显著降低伴有严重阴茎下弯的近端尿道下裂的尿瘘发生率。然而,这可能会增加对不需要分期手术的儿童进行手术的次数。尽管我们无法通过本研究证实,但我们认为两阶段尿道成形术的必要性应根据龟头发育情况、阴茎弯曲严重程度和尿道缺损长度来确定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9d9/8107854/c8650b21100e/tp-10-04-843-f1.jpg

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